Literature DB >> 1080375

[The effect of human leukocyte interteron (HIF) on experimental viral keratitis in monkeys (author's transl)].

D Neumann-Haefelin, B Shrestha.   

Abstract

12 african green monkeys were inoculated in both eyes with herpes simplex virus typ 1 and 16 rhesus monkeys with vaccinia virus. The right eyes were treated with human leukocyte interferon (HIF) while the left eyes served as controls and showed the typical keratitis, 7 out of 8 herpes eyes and all 9 vaccinia eyes which were treated prophylactically or simultaneiously with HIF showed no signs of disease. When HIF was given later in the course of the infection the keratitis was either little influenced or not modified at all. The reasons are discussed.

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Year:  1975        PMID： 1080375     DOI： 10.1007/bf00414939

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  9 in total

1.  TREATMENT OF DENDRITIC KERATITIS WITH INTERFERON.

Authors:  V TOMMILA
Journal:  Acta Ophthalmol (Copenh)       Date:  1963

2.  Effect of interferon on experimental vaccinia and herpes-simplex virus infections in rabbits' eyes.

Authors:  K CANTELL; V TOMMILA
Journal:  Lancet       Date:  1960-09-24       Impact factor: 79.321

3.  Vaccinial keratitis treated with interferon.

Authors:  B R JONES; J E GALBRAITH; M K AL-HUSSAINI
Journal:  Lancet       Date:  1962-04-28       Impact factor: 79.321

4.  Further studies on an inhibitor of viral activity appearing in infected cell cultures and its role in chronic viral infections.

Authors:  M HO; J F ENDERS
Journal:  Virology       Date:  1959-11       Impact factor: 3.616

5.  Virus interference. I. The interferon.

Authors:  A ISAACS; J LINDENMANN
Journal:  Proc R Soc Lond B Biol Sci       Date:  1957-09-12

6.  Difference in interferon response and protection from ocular virus infection in rabbits and monkeys.

Authors:  H E Kaufman; E D Ellison; Y M Centifanto
Journal:  Am J Ophthalmol       Date:  1972-07       Impact factor: 5.258

7.  Interferon induction in rabbit and human tears.

Authors:  Y M Centifanto; R M Goorha; H E Kaufman
Journal:  Am J Ophthalmol       Date:  1970-12       Impact factor: 5.258

8.  Effect of exogenous interferon on herpetic keratitis in rabbits and monkeys.

Authors:  H E Kaufman; J Sugar; E D Varnell
Journal:  Invest Ophthalmol       Date:  1973-05

9.  [Research on the preventive action of a viral preparation with interferring action in experimental herpetic keratitis in rabbits].

Authors:  P Cilotti; R Brancato
Journal:  Ann Ottalmol Clin Ocul       Date:  1967-05
  9 in total
  1 in total

1.  Successful treatment of dendritic keratitis with human leukocyte interferon. A controlled clinical study.

Authors:  R Sundmacher; D Neumann-Haefelin; K Cantell
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1976-11-18
  1 in total

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