A M Gülmezoglu1, G J Hofmeyr. 1. Special Department of Research, Development and Research Training in Human Reproduction, UNDP/UNFPA/WHO/World Bank, World Health Organisation, Geneva 27, Switzerland, CH-1211. gulmezoglum@who.ch
Abstract
BACKGROUND: Failure of the normal expansion of plasma volume in the mother is associated with impaired fetal growth and pre-eclampsia. OBJECTIVES: The objective of this review was to assess the effects of plasma volume expansion for suspected impaired fetal growth. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register. Date of last search: December 1999. SELECTION CRITERIA: Randomized or quasi-randomized trials of plasma volume expansion compared to no plasma volume expansion in women with suspected impaired fetal growth. DATA COLLECTION AND ANALYSIS: Trial quality was assessed. MAIN RESULTS: No studies were included. REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the use of plasma volume expansion for suspected impaired fetal growth.
BACKGROUND: Failure of the normal expansion of plasma volume in the mother is associated with impaired fetal growth and pre-eclampsia. OBJECTIVES: The objective of this review was to assess the effects of plasma volume expansion for suspected impaired fetal growth. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register and the Cochrane Controlled Trials Register. Date of last search: December 1999. SELECTION CRITERIA: Randomized or quasi-randomized trials of plasma volume expansion compared to no plasma volume expansion in women with suspected impaired fetal growth. DATA COLLECTION AND ANALYSIS: Trial quality was assessed. MAIN RESULTS: No studies were included. REVIEWER'S CONCLUSIONS: There is not enough evidence to evaluate the use of plasma volume expansion for suspected impaired fetal growth.