| Literature DB >> 10791395 |
Abstract
The taxanes are anticancer cytotoxics that stabilise cellular microtubules. Two members, paclitaxel and docetaxel have substantial activity. One or both agents are widely accepted as evidence-based components of therapy for advanced breast, lung, and ovarian carcinomas. Paclitaxel has recently been approved in the USA for the adjuvant treatment of early stage node-positive breast carcinoma.Entities:
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Year: 2000 PMID: 10791395 DOI: 10.1016/S0140-6736(00)02074-2
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321