Literature DB >> 10773497

The anti-bacterial action of diclofenac shown by inhibition of DNA synthesis.

S G Dastidar1, K Ganguly, K Chaudhuri, A N Chakrabarty.   

Abstract

Most strains of Gram-positive and Gram-negative bacteria were inhibited by 50-100 mg/l of the anti-inflammatory agent, diclofenac sodium (Dc). In vivo test using 30 or 50 microg Dc per 20 g mouse (Swiss Albino variety) significantly (P <0.001) protected the animals when challenged with 50 MLD of a virulent Salmonella typhimurium. The anti-bacterial action of Dc was found to be due to inhibition of DNA synthesis which was demonstrated using 2 micro Ci (3H) deoxythymidine uptake.

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Year:  2000        PMID： 10773497     DOI： 10.1016/s0924-8579(99)00159-4

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN： 0924-8579            Impact factor:   5.283


  29 in total

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Review 2.  Antimicrobial Effects of Antipyretics.

Authors:  Petra Zimmermann; Nigel Curtis
Journal:  Antimicrob Agents Chemother       Date:  2017-03-24       Impact factor: 5.191

Review 3.  The comparative efficacy and safety of topical non-steroidal anti-inflammatory drugs for the treatment of anterior chamber inflammation after cataract surgery: a systematic review and network meta-analysis.

Authors:  Ping Duan; Yong Liu; Jiawen Li
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-01-27       Impact factor: 3.117

4.  One-step grafting of temperature-and pH-sensitive (N-vinylcaprolactam-co-4-vinylpyridine) onto silicone rubber for drug delivery.

Authors:  Victor H Pino-Ramos; Carmen Alvarez-Lorenzo; Angel Concheiro; Emilio Bucio
Journal:  Des Monomers Polym       Date:  2016-09-20       Impact factor: 2.650

5.  Large-Scale and Rapid Preparation of Nanofibrous Meshes and Their Application for Drug-Loaded Multilayer Mucoadhesive Patch Fabrication for Mouth Ulcer Treatment.

Authors:  Liang Wei; Shaohua Wu; Wen Shi; Amy L Aldrich; Tammy Kielian; Mark A Carlson; Runjun Sun; Xiaohong Qin; Bin Duan
Journal:  ACS Appl Mater Interfaces       Date:  2019-08-05       Impact factor: 9.229

6.  Antibiofilm potential over time of a tricalcium silicate material and its association with sodium diclofenac.

Authors:  M Ruiz-Linares; C Solana; P Baca; M T Arias-Moliz; C M Ferrer-Luque
Journal:  Clin Oral Investig       Date:  2021-10-28       Impact factor: 3.573

Review 7.  The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target.

Authors:  K Mazumdar; S G Dastidar; J H Park; N K Dutta
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-04-28       Impact factor: 3.267

8.  Nonsteroidal antiinflammatory drugs alter antibiotic susceptibility and expression of virulence-related genes and protein A of Staphylococcus aureus

Authors:  İsmail Öztürk; Yasemin Eraç; Petek Ballar Kırmızibayrak; Şafak Ermertcan
Journal:  Turk J Med Sci       Date:  2021-04-30       Impact factor: 0.973

9.  Antibacterial Effect of Diclofenac Sodium on Enterococcus faecalis.

Authors:  Amin Salem-Milani; Esrafil Balaei-Gajan; Saeed Rahimi; Zohreh Moosavi; Ardalan Abdollahi; Parvin Zakeri-Milani; Mehrdad Bolourian
Journal:  J Dent (Tehran)       Date:  2013-01-31

10.  A comparative analysis of in vitro and in vivo efficacies of the enantiomers of thioridazine and its racemate.

Authors:  Jørn B Christensen; Oliver Hendricks; Shaswati Chaki; Sayanti Mukherjee; Ayan Das; Tapan K Pal; Sujata G Dastidar; Jette E Kristiansen
Journal:  PLoS One       Date:  2013-03-07       Impact factor: 3.240
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