Literature DB >> 10772718

Synthesis of 4'-thio-beta-D-arabinofuranosylcytosine (4'-thio-ara-C) and comparison of its anticancer activity with that of ara-C.

K N Tiwari1, A T Shortnacy-Fowler, L Cappellacci, W B Parker, W R Waud, J A Montgomery, J A Secrist.   

Abstract

4'-thio-beta-D-arabinofuranosylcytosine was synthesized by a facile route in high yields. It was evaluated for antitumor activity against a panel of human tumors, both in vitro and in vivo.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 10772718     DOI： 10.1080/15257770008033012

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  5 in total

1.  Lack of in vivo cross-resistance with 4'-thio-ara-C against drug-resistant murine P388 and L1210 leukemias.

Authors:  William R Waud; Karen S Gilbert; John A Secrist
Journal:  Cancer Chemother Pharmacol       Date:  2010-11-11       Impact factor: 3.333

2.  Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides.

Authors:  Mark N Prichard; Debra C Quenelle; Caroll B Hartline; Emma A Harden; Geraldine Jefferson; Samuel L Frederick; Shannon L Daily; Richard J Whitley; Kamal N Tiwari; Joseph A Maddry; John A Secrist; Earl R Kern
Journal:  Antimicrob Agents Chemother       Date:  2009-09-21       Impact factor: 5.191

Review 3.  Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.

Authors:  Lars Petter Jordheim; David Durantel; Fabien Zoulim; Charles Dumontet
Journal:  Nat Rev Drug Discov       Date:  2013-06       Impact factor: 84.694

4.  Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections.

Authors:  Earl R Kern; Mark N Prichard; Debra C Quenelle; Kathy A Keith; Kamal N Tiwari; Joseph A Maddry; John A Secrist
Journal:  Antimicrob Agents Chemother       Date:  2008-11-24       Impact factor: 5.191

5.  Discovery of a Novel Template, 7-Substituted 7-Deaza-4'-Thioadenosine Derivatives as Multi-Kinase Inhibitors.

Authors:  Karishma K Mashelkar; Woong Sub Byun; Hyejin Ko; Kisu Sung; Sushil K Tripathi; Seungchan An; Yun A Yum; Jee Youn Kwon; Minjae Kim; Gibae Kim; Eun-Ji Kwon; Hyuk Woo Lee; Minsoo Noh; Sang Kook Lee; Lak Shin Jeong
Journal:  Pharmaceuticals (Basel)       Date:  2021-12-10
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.