Literature DB >> 10762047

Isoniazid-related copper(II) and nickel(II) complexes with antimycobacterial in vitro activity. Part 9.

B Bottari1, R Maccari, F Monforte, R Ottanà, E Rotondo, M G Vigorita.   

Abstract

Isonicotinoylhydrazones 1, obtained by the primary antituberculous agent Isoniazid, have been used as monoanionic ligands (L) to prepare copper(II) 2 and nickel(II) 3 octahedral complexes of stoichiometry [MeL2(H2O)2]. Their antimycobacterial in vitro activity was evaluated against Mycobacterium tuberculosis H37Rv in comparison with the ligands. Complexes 2a, 2b, 2f, 3b, 3d and 3g displayed MIC values < or = 0.2 microg/mL.

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Year:  2000        PMID： 10762047     DOI： 10.1016/s0960-894x(00)00058-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity.

Authors:  Alex G Dalecki; Aruni P Malalasekera; Kaitlyn Schaaf; Olaf Kutsch; Stefan H Bossmann; Frank Wolschendorf
Journal:  Metallomics       Date:  2016-03-03       Impact factor: 4.526

2.  In vitro antimycobacterial activities of 2'-monosubstituted isonicotinohydrazides and their cyanoborane adducts.

Authors:  Rosanna Maccari; Rosaria Ottanà; Francesca Monforte; Maria Gabriella Vigorita
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

3.  Synthesis, Biological, Spectral, and Thermal Investigations of Cobalt(II) and Nickel(II) Complexes of N-Isonicotinamido -2',4'-Dichlorobenzalaldimine.

Authors:  Ram K Agarwal; Deepak Sharma; Lakshman Singh; Himanshu Agarwal
Journal:  Bioinorg Chem Appl       Date:  2006-06-06       Impact factor: 7.778

4.  ON donor tethered copper (II) and vanadium (V) complexes as efficacious anti-TB and anti-fungal agents with spectroscopic approached HSA interactions.

Authors:  Anamika Sinha; Riya Chaudhary; Dinesh S Reddy; Manasa Kongot; Mahantesh M Kurjogi; Amit Kumar
Journal:  Heliyon       Date:  2022-08-11

5.  End-to-End Thiocyanato-Bridged Helical Chain Polymer and Dichlorido-Bridged Copper(II) Complexes with a Hydrazone Ligand: Synthesis, Characterisation by Electron Paramagnetic Resonance and Variable-Temperature Magnetic Studies, and Inhibitory Effects on Human Colorectal Carcinoma Cells.

Authors:  Kuheli Das; Amitabha Datta; Chittaranjan Sinha; Jui-Hsien Huang; Eugenio Garribba; Ching-Sheng Hsiao; Chin-Lin Hsu
Journal:  ChemistryOpen       Date:  2012-03-13       Impact factor: 2.911

6.  In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis.

Authors:  Patricia B da Silva; Paula C de Souza; Giovana Maria Fioramonti Calixto; Erica de O Lopes; Regina C G Frem; Adelino V G Netto; Antonio E Mauro; Fernando R Pavan; Marlus Chorilli
Journal:  Int J Mol Sci       Date:  2016-05-17       Impact factor: 5.923

Review 7.  Copper Coordination Compounds as Biologically Active Agents.

Authors:  Olga Krasnovskaya; Alexey Naumov; Dmitry Guk; Peter Gorelkin; Alexander Erofeev; Elena Beloglazkina; Alexander Majouga
Journal:  Int J Mol Sci       Date:  2020-05-31       Impact factor: 5.923
  7 in total

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