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Literature DB >> 10755952

Genomic medicine and the future of health care.

Abstract

Genomic technologies and computational advances are leading to an information revolution in biology and medicine. Simulations of molecular processes in cells and predictions of drug effects in humans will advance pharmaceutical research and speed up clinical trials. Computational prognostics and diagnostics that combine with genotyping and molecular profiling may soon cause fundamental changes in the practice of health care.

Entities: Species

Mesh：

Year: 2000 PMID： 10755952 DOI： 10.1126/science.287.5460.1977

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

24 in total

1. Bioinformatics and medical informatics: collaborations on the road to genomic medicine?

Authors: Victor Maojo; Casimir A Kulikowski
Journal: J Am Med Inform Assoc Date: 2003-08-04 Impact factor: 4.497

Review 2. Drug-gene interactions between genetic polymorphisms and antihypertensive therapy.

Authors: Hedi Schelleman; Bruno H Ch Stricker; Anthonius De Boer; Abraham A Kroon; Monique W M Verschuren; Cornelia M Van Duijn; Bruce M Psaty; Olaf H Klungel
Journal: Drugs Date: 2004 Impact factor: 9.546

3. Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors.

Authors: H Schelleman; O H Klungel; C M van Duijn; J C M Witteman; A Hofman; A de Boer; B H Ch Stricker
Journal: Br J Clin Pharmacol Date: 2005-04 Impact factor: 4.335

Review 4. Diamond and biology.

Authors: Christoph E Nebel; Dongchan Shin; Bohuslav Rezek; Norio Tokuda; Hiroshi Uetsuka; Hideyuki Watanabe
Journal: J R Soc Interface Date: 2007-06-22 Impact factor: 4.118

Genomic medicine and the future of health care.

1. Bioinformatics and medical informatics: collaborations on the road to genomic medicine?

Review 2. Drug-gene interactions between genetic polymorphisms and antihypertensive therapy.

3. Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors.

Review 4. Diamond and biology.

5. Logical schema acquisition from text-based sources for structured and non-structured biomedical sources integration.

6. Nanobiosensors: optofluidic, electrical and mechanical approaches to biomolecular detection at the nanoscale.

Review 7. Resveratrol: Biological and pharmaceutical properties as anticancer molecule.

8. Engineering a customized nanodrug delivery system at the cellular level for targeted cancer therapy.

9. Minimally perturbing a gene regulatory network to avoid a disease phenotype: the glioma network as a test case.

10. Label-free biomarker detection from whole blood.