Literature DB >> 10755395

A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer.

I E Young1, K M Kurian, M A MacKenzie, I H Kunkler, B B Cohen, M L Hooper, A H Wyllie, C M Steel.   

Abstract

The CYP19 gene codes for the aromatase enzyme that is involved in the synthesis of oestrogens. This case-control study examines the relationship between a tetranucleotide repeat sequence in the CYP19 gene and the development of male breast cancer. No significant differences were found between male breast cancer cases and controls.

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Year:  2000        PMID： 10755395      PMCID： PMC2374487          DOI： 10.1054/bjoc.1999.1085

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  8 in total

1.  CARCINOMA OF MALE BREAST IN ASSOCIATION WITH THE KLINEFELTER SYNDROME.

Authors:  A W JACKSON; S MULDAL; C H OCKEY; P J O'CONNOR
Journal:  Br Med J       Date:  1965-01-23

2.  Tetranucleotide repeat polymorphism at the human aromatase cytochrome P-450 gene (CYP19).

Authors:  M H Polymeropoulos; H Xiao; D S Rath; C R Merril
Journal:  Nucleic Acids Res       Date:  1991-01-11       Impact factor: 16.971

3.  Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.

Authors:  G D Means; M S Mahendroo; C J Corbin; J M Mathis; F E Powell; C R Mendelson; E R Simpson
Journal:  J Biol Chem       Date:  1989-11-15       Impact factor: 5.157

4.  Combined polymorphism associated with a 3-bp deletion in the 5'-flanking region of a tetrameric short tandem repeat at the CYP19 locus.

Authors:  K Kurosaki; H Saitoh; H Oota; Y Watanabe; M Kiuchi; S Ueda
Journal:  Nihon Hoigaku Zasshi       Date:  1997-06

5.  Aromatase and steroid receptors in gynecomastia and male breast carcinoma: an immunohistochemical study.

Authors:  H Sasano; M Kimura; S Shizawa; N Kimura; H Nagura
Journal:  J Clin Endocrinol Metab       Date:  1996-08       Impact factor: 5.958

6.  A rare CYP19 (aromatase) variant may increase the risk of breast cancer.

Authors:  V N Kristensen; T I Andersen; A Lindblom; B Erikstein; P Magnus; A L Børresen-Dale
Journal:  Pharmacogenetics       Date:  1998-02

7.  Constitutional genetic variation at the human aromatase gene (Cyp19) and breast cancer risk.

Authors:  N Siegelmann-Danieli; K H Buetow
Journal:  Br J Cancer       Date:  1999-02       Impact factor: 7.640

8.  A polymorphism in the CYP17 gene is associated with male breast cancer.

Authors:  I E Young; K M Kurian; C Annink; I H Kunkler; V A Anderson; B B Cohen; M L Hooper; A H Wyllie; C M Steel
Journal:  Br J Cancer       Date:  1999-09       Impact factor: 7.640
  8 in total

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