Literature DB >> 10487625

A polymorphism in the CYP17 gene is associated with male breast cancer.

I E Young1, K M Kurian, C Annink, I H Kunkler, V A Anderson, B B Cohen, M L Hooper, A H Wyllie, C M Steel.   

Abstract

The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.

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Year:  1999        PMID: 10487625      PMCID: PMC2374358          DOI: 10.1038/sj.bjc.6690663

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  17 in total

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Review 3.  The Epidemiology of Male Breast Cancer.

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7.  Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association study.

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8.  A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer.

Authors:  I E Young; K M Kurian; M A MacKenzie; I H Kunkler; B B Cohen; M L Hooper; A H Wyllie; C M Steel
Journal:  Br J Cancer       Date:  2000-04       Impact factor: 7.640

9.  The effect of antineoplastic drugs in a male spontaneous mammary tumor model.

Authors:  Stephanie N Shishido; Emma B Faulkner; Amanda Beck; Thu A Nguyen
Journal:  PLoS One       Date:  2013-06-03       Impact factor: 3.240

10.  CYP17 promoter polymorphism and breast cancer risk in males and females in relation to BRCA2 status.

Authors:  K Gudmundsdottir; S Thorlacius; J G Jonasson; B F Sigfusson; L Tryggvadottir; J E Eyfjord
Journal:  Br J Cancer       Date:  2003-03-24       Impact factor: 7.640

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