Literature DB >> 10753780

The uniqueness of the imprinting mechanism.

F Sleutels1, D P Barlow, R Lyle.   

Abstract

An epigenetic imprinting mechanism that is based on a gamete-specific methylation imprint restricts expression of a subset of mammalian genes to one parental chromosome. Recent results suggest that imprints may act only indirectly to induce monoallelic expression of coding genes. Instead, atypical non-coding RNAs appear to be a primary target of the imprints, and their parental-specific repression correlates with parental-specific expression of linked coding genes.

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Year:  2000        PMID： 10753780     DOI： 10.1016/s0959-437x(00)00062-9

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  25 in total

1.  The imprinted gene and parent-of-origin effect database.

Authors:  I M Morison; C J Paton; S D Cleverley
Journal:  Nucleic Acids Res       Date:  2001-01-01       Impact factor: 16.971

2.  Non-coding RNAs: the architects of eukaryotic complexity.

Authors:  J S Mattick
Journal:  EMBO Rep       Date:  2001-11       Impact factor: 8.807

3.  An intragenic methylated region in the imprinted Igf2 gene augments transcription.

Authors:  A Murrell; S Heeson; L Bowden; M Constância; W Dean; G Kelsey; W Reik
Journal:  EMBO Rep       Date:  2001-11-21       Impact factor: 8.807

4.  Random monoallelic expression of three genes clustered within 60 kb of mouse t complex genomic DNA.

Authors:  Y Sano; T Shimada; H Nakashima; R H Nicholson; J F Eliason; T A Kocarek; M S Ko
Journal:  Genome Res       Date:  2001-11       Impact factor: 9.043

5.  Cis-acting variation in the expression of a high proportion of genes in human brain.

Authors:  Nicholas J Bray; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Journal:  Hum Genet       Date:  2003-05-01       Impact factor: 4.132

Review 6.  Non-coding RNAs in the nervous system.

Authors:  Mark F Mehler; John S Mattick
Journal:  J Physiol       Date:  2006-06-29       Impact factor: 5.182

Review 7.  rRNA gene silencing and nucleolar dominance: insights into a chromosome-scale epigenetic on/off switch.

Authors:  Sasha Preuss; Craig S Pikaard
Journal:  Biochim Biophys Acta       Date:  2007-03-12

8.  Investigation of elements sufficient to imprint the mouse Air promoter.

Authors:  F Sleutels; D P Barlow
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

9.  Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements.

Authors:  Florian M Pauler; Stefan H Stricker; Katarzyna E Warczok; Denise P Barlow
Journal:  Genome Res       Date:  2005-10       Impact factor: 9.043

10.  A novel class of tests for the detection of mitochondrial DNA-mutation involvement in diseases.

Authors:  Fengzhu Sun; Jing Cui; Haralambos Gavras; Faina Schwartz
Journal:  Am J Hum Genet       Date:  2003-04-30       Impact factor: 11.025
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