| Literature DB >> 10747158 |
J H Song1, J W Yang, J H Jin, S W Kim, C K Kim, H Lee, K R Peck, S Kim, N Y Lee, M R Jacobs, P C Appelbaum.
Abstract
Pulsed-field gel electrophoresis, ribotyping, and fingerprinting analysis of 22 invasive isolates of multidrug-resistant (MDR) pneumococci from Korea showed that 59 to 82% were genetically related. DNA sequencing of the PBP 2B gene showed relatively uniform alterations in nucleotides (5.4 to 7.8%) and amino acids (3.0 to 4. 3%), while Asn-276-->Lys, Arg-285-->Cys and Ser-305-->Phe substitutions were unique to Korean MDR strains, suggesting the spread of a few epidemic clones of resistant pneumococci within Korea.Entities:
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Year: 2000 PMID: 10747158 PMCID: PMC86510
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948