Literature DB >> 10737906

Chemical stability of nucleic acid-derived drugs.

D Pogocki1, C Schöneich.   

Abstract

Nucleic acid-derived drugs exhibit both chemical and physical instability. This mini-review focuses on the prevalent hydrolytic and oxidative pathways of chemical degradation as they are affected by various endogenous (primary structure, chemical modifications in bases, sugars and phosphate residues) and exogenous (pH, buffer concentration, metal cation presence, oxygen presence) factors. Copyright 2000 Wiley-Liss, Inc.

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Year:  2000        PMID： 10737906     DOI： 10.1002/(SICI)1520-6017(200004)89:4<443::AID-JPS2>3.0.CO;2-W

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  12 in total

1.  Impact of long-term storage on stability of standard DNA for nucleic acid-based methods.

Authors:  Barbara Röder; Karin Frühwirth; Claus Vogl; Martin Wagner; Peter Rossmanith
Journal:  J Clin Microbiol       Date:  2010-09-01       Impact factor: 5.948

2.  Metal contaminants promote degradation of lipid/DNA complexes during lyophilization.

Authors:  Marion d C Molina; Thomas J Anchordoquy
Journal:  Biochim Biophys Acta       Date:  2006-12-08

Review 3.  The emerging field of RNA nanotechnology.

Authors:  Peixuan Guo
Journal:  Nat Nanotechnol       Date:  2010-11-21       Impact factor: 39.213

Review 4.  Uncertainties in synthetic DNA-based data storage.

Authors:  Chengtao Xu; Chao Zhao; Biao Ma; Hong Liu
Journal:  Nucleic Acids Res       Date:  2021-06-04       Impact factor: 16.971

Review 5.  Engineering DNA vaccines against infectious diseases.

Authors:  Jihui Lee; Shreedevi Arun Kumar; Yong Yu Jhan; Corey J Bishop
Journal:  Acta Biomater       Date:  2018-08-31       Impact factor: 8.947

Review 6.  mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability.

Authors:  Linde Schoenmaker; Dominik Witzigmann; Jayesh A Kulkarni; Rein Verbeke; Gideon Kersten; Wim Jiskoot; Daan J A Crommelin
Journal:  Int J Pharm       Date:  2021-04-09       Impact factor: 6.510

7.  A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems.

Authors:  Meredith Packer; Dipendra Gyawali; Ravikiran Yerabolu; Joseph Schariter; Phil White
Journal:  Nat Commun       Date:  2021-11-22       Impact factor: 14.919

Review 8.  The Potential of Nanomedicine to Unlock the Limitless Applications of mRNA.

Authors:  Laura Taina-González; María de la Fuente
Journal:  Pharmaceutics       Date:  2022-02-21       Impact factor: 6.321

9.  Chain and conformation stability of solid-state DNA: implications for room temperature storage.

Authors:  Jacques Bonnet; Marthe Colotte; Delphine Coudy; Vincent Couallier; Joseph Portier; Bénédicte Morin; Sophie Tuffet
Journal:  Nucleic Acids Res       Date:  2009-12-07       Impact factor: 16.971

10.  High DNA stability in white blood cells and buffy coat lysates stored at ambient temperature under anoxic and anhydrous atmosphere.

Authors:  Anne-Lise Fabre; Aurélie Luis; Marthe Colotte; Sophie Tuffet; Jacques Bonnet
Journal:  PLoS One       Date:  2017-11-30       Impact factor: 3.240
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