Literature DB >> 10733612

Functional derivatives of 5-benzo[1, 3]dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde and evaluation of leishmanicidal activity.

P Vanelle1, J Meuche, J Maldonado, M P Crozet, F Delmas, P Timon-David.   

Abstract

New imidazole derivatives were obtained after subjecting 5-benzo[1, 3]dioxol-5-yl-1-methyl-1H-imidazole-2-carbaldehyde to a Knoevenagel reaction. Some of these compounds exhibit significant in vitro leishmanicidal activity.

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Year:  2000        PMID: 10733612     DOI: 10.1016/s0223-5234(00)00106-9

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN: 0223-5234            Impact factor:   6.514


  1 in total

1.  5-Nitroimidazole drugs effective against metronidazole-resistant Trichomonas vaginalis and Giardia duodenalis.

Authors:  Jacqueline A Upcroft; Linda A Dunn; Janelle M Wright; Kamel Benakli; Peter Upcroft; Patrice Vanelle
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

  1 in total

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