Literature DB >> 10728348

Cardiac fatty acid uptake and transport in health and disease.

G J van der Vusse1, M van Bilsen, J F Glatz.   

Abstract

Fatty acids are important energy donors for the healthy heart. These substrates are supplied to the myocardium bound to albumin to overcome their low solubility in aqueous solutions such as blood plasma. Transport from the microvascular compartment to the mitochondria inside the cardiomyocytes is most likely a combination of passive and protein-mediated diffusion. Alterations in tissue content of fatty acid-transport proteins may contribute to myocardial diseases such as the diabetic heart, and cardiac hypertrophy and failure.

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Year:  2000        PMID： 10728348     DOI： 10.1016/s0008-6363(99)00263-1

Source DB:  PubMed          Journal:  Cardiovasc Res        ISSN： 0008-6363            Impact factor:   10.787


  87 in total

Review 1.  Involvement of membrane-associated proteins in the acute regulation of cellular fatty acid uptake.

Authors:  J F Glatz; J J Luiken; A Bonen
Journal:  J Mol Neurosci       Date:  2001 Apr-Jun       Impact factor: 3.444

Review 2.  Critical steps in cellular fatty acid uptake and utilization.

Authors:  Ger J van der Vusse; Marc van Bilsen; Jan F C Glatz; Danny M Hasselbaink; Joost J F P Luiken
Journal:  Mol Cell Biochem       Date:  2002-10       Impact factor: 3.396

3.  Mitofusins are required for angiogenic function and modulate different signaling pathways in cultured endothelial cells.

Authors:  Jesse J Lugus; Gladys A Ngoh; Markus M Bachschmid; Kenneth Walsh
Journal:  J Mol Cell Cardiol       Date:  2011-08-02       Impact factor: 5.000

4.  Transport of Free Fatty Acids from Plasma to the Endothelium of Cardiac Muscle: A Theoretical Study.

Authors:  Efrath Barta
Journal:  J Membr Biol       Date:  2015-04-03       Impact factor: 1.843

5.  Circumferential wall tension due to hypertension plays a pivotal role in aorta remodelling.

Authors:  Cibele M Prado; Marcos A Rossi
Journal:  Int J Exp Pathol       Date:  2006-12       Impact factor: 1.925

6.  Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation.

Authors:  Kenta Kuramoto; Tomoo Okamura; Tomohiro Yamaguchi; Tomoe Y Nakamura; Shigeo Wakabayashi; Hidetaka Morinaga; Masatoshi Nomura; Toshihiko Yanase; Kinya Otsu; Nobuteru Usuda; Shigenobu Matsumura; Kazuo Inoue; Tohru Fushiki; Yumiko Kojima; Takeshi Hashimoto; Fumie Sakai; Fumiko Hirose; Takashi Osumi
Journal:  J Biol Chem       Date:  2012-04-24       Impact factor: 5.157

7.  Fatty acid synthase modulates homeostatic responses to myocardial stress.

Authors:  Babak Razani; Haixia Zhang; P Christian Schulze; Joel D Schilling; John Verbsky; Irfan J Lodhi; Veli K Topkara; Chu Feng; Trey Coleman; Attila Kovacs; Daniel P Kelly; Jeffrey E Saffitz; Gerald W Dorn; Colin G Nichols; Clay F Semenkovich
Journal:  J Biol Chem       Date:  2011-07-08       Impact factor: 5.157

8.  Innate short-circuiting of mitochondrial metabolism in cardiac hypertrophy: identification of novel consequences of enhanced anaplerosis.

Authors:  Michael N Sack
Journal:  Circ Res       Date:  2009-03-27       Impact factor: 17.367

Review 9.  Effects of exercise on the fatty-acid composition of blood and tissue lipids.

Authors:  Michalis G Nikolaidis; Vassilis Mougios
Journal:  Sports Med       Date:  2004       Impact factor: 11.136

Review 10.  Transcriptional regulation of energy substrate metabolism in normal and hypertrophied heart.

Authors:  Rong Tian
Journal:  Curr Hypertens Rep       Date:  2003-12       Impact factor: 5.369
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