Literature DB >> 10720355

Incidence and types of preventable adverse events in elderly patients: population based review of medical records.

E J Thomas1, T A Brennan.   

Abstract

OBJECTIVE: To determine the incidence and types of preventable adverse events in elderly patients.
DESIGN: Review of random sample of medical records in two stage process by nurses and physicians to detect adverse events. Two study investigators then judged preventability.
SETTING: Hospitals in US states of Utah and Colorado, excluding psychiatric and Veterans Administration hospitals.
SUBJECTS: 15 000 hospitalised patients discharged in 1992. MAIN OUTCOME MEASURES: Incidence of preventable adverse events (number of preventable events per 100 discharges) in elderly patients (>/=65 years old) and non-elderly patients (16-64 years).
RESULTS: When results were extrapolated to represent all discharges in 1992 in both states, non-elderly patients had 8901 adverse events (incidence 2.80% (SE 0.18%)) compared with 7419 (5.29% (0.37%)) among elderly patients (P=0.001). Non-elderly patients had 5038 preventable adverse events (incidence 1.58% (0.14%)) compared with 4134 (2.95% (0.28%)) in elderly patients (P=0.001). Elderly patients had a higher incidence of preventable events related to medical procedures (such as thoracentesis, cardiac catheterisation) (0.69% (0.14%) v 0.13% (0.04%)), preventable adverse drug events (0.63% (0.14%) v 0.17% (0.05%)), and preventable falls (0.10% (0.06%) v 0.01% (0.02%)). In multivariate analyses, adjusted for comorbid illnesses and case mix, age was not an independent predictor of preventable adverse events.
CONCLUSIONS: Preventable adverse events were more common among elderly patients, probably because of the clinical complexity of their care rather than age based discrimination. Preventable adverse drug events, events related to medical procedures, and falls were especially common in elderly patients and should be targets for efforts to prevent errors.

Entities:  

Mesh:

Year:  2000        PMID: 10720355      PMCID: PMC27315          DOI: 10.1136/bmj.320.7237.741

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  11 in total

1.  The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II.

Authors:  L L Leape; T A Brennan; N Laird; A G Lawthers; A R Localio; B A Barnes; L Hebert; J P Newhouse; P C Weiler; H Hiatt
Journal:  N Engl J Med       Date:  1991-02-07       Impact factor: 91.245

2.  How should clinical care of the aged differ?

Authors:  N M Resnick; E R Marcantonio
Journal:  Lancet       Date:  1997-10-18       Impact factor: 79.321

3.  Adverse drug events in hospitalized elderly.

Authors:  S L Gray; M Sager; M R Lestico; M Jalaluddin
Journal:  J Gerontol A Biol Sci Med Sci       Date:  1998-01       Impact factor: 6.053

4.  Hospital-acquired complications in a randomized controlled clinical trial of a geriatric consultation team.

Authors:  P M Becker; L J McVey; C C Saltz; J R Feussner; H J Cohen
Journal:  JAMA       Date:  1987-05-01       Impact factor: 56.272

5.  Incidence of adverse drug events and potential adverse drug events. Implications for prevention. ADE Prevention Study Group.

Authors:  D W Bates; D J Cullen; N Laird; L A Petersen; S D Small; D Servi; G Laffel; B J Sweitzer; B F Shea; R Hallisey
Journal:  JAMA       Date:  1995-07-05       Impact factor: 56.272

6.  Incidence and types of adverse events and negligent care in Utah and Colorado.

Authors:  E J Thomas; D M Studdert; H R Burstin; E J Orav; T Zeena; E J Williams; K M Howard; P C Weiler; T A Brennan
Journal:  Med Care       Date:  2000-03       Impact factor: 2.983

7.  Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.

Authors:  D C Classen; S L Pestotnik; R S Evans; J F Lloyd; J P Burke
Journal:  JAMA       Date:  1997 Jan 22-29       Impact factor: 56.272

8.  Iatrogenic illness on a general medical service at a university hospital.

Authors:  K Steel; P M Gertman; C Crescenzi; J Anderson
Journal:  N Engl J Med       Date:  1981-03-12       Impact factor: 91.245

9.  Hospital falls: a persistent problem.

Authors:  V R Morgan; J H Mathison; J C Rice; D I Clemmer
Journal:  Am J Public Health       Date:  1985-07       Impact factor: 9.308

10.  Iatrogenic disease in hospitalized elderly veterans.

Authors:  D Jahnigen; C Hannon; L Laxson; F M LaForce
Journal:  J Am Geriatr Soc       Date:  1982-06       Impact factor: 5.562

View more
  78 in total

1.  Medical errors: a common problem.

Authors:  K G Alberti
Journal:  BMJ       Date:  2001-03-03

2.  Learning from malpractice claims about negligent, adverse events in primary care in the United States.

Authors:  R L Phillips; L A Bartholomew; S M Dovey; G E Fryer; T J Miyoshi; L A Green
Journal:  Qual Saf Health Care       Date:  2004-04

Review 3.  Preventability of drug-related harms - part I: a systematic review.

Authors:  Robin E Ferner; Jeffrey K Aronson
Journal:  Drug Saf       Date:  2010-11-01       Impact factor: 5.606

4.  Quality indicators for in-hospital pharmaceutical care of Dutch elderly patients: development and validation of an ACOVE-based quality indicator set.

Authors:  Peter C Wierenga; Joanna E Klopotowska; Susanne M Smorenburg; Hendrikus J van Kan; Yuma A Bijleveld; Marcel G Dijkgraaf; Sophia E de Rooij
Journal:  Drugs Aging       Date:  2011-04-01       Impact factor: 3.923

5.  The registration of complications in surgery: a learning curve.

Authors:  Eelco J Veen; Maryska L G Janssen-Heijnen; Loek P H Leenen; Jan A Roukema
Journal:  World J Surg       Date:  2005-03       Impact factor: 3.352

6.  Are incorrectly used drugs more frequently involved in adverse drug reactions? A prospective study.

Authors:  A P Jonville-Béra; F Béra; E Autret-Leca
Journal:  Eur J Clin Pharmacol       Date:  2005-04-12       Impact factor: 2.953

7.  Using a sentinel adverse incident audit on a Medicine for the Elderly ward.

Authors:  M D Witham; P M Jenkins; M E T McMurdo
Journal:  Qual Saf Health Care       Date:  2006-12

Review 8.  Understanding Decision Making in Critical Care.

Authors:  Geoffrey K Lighthall; Cristina Vazquez-Guillamet
Journal:  Clin Med Res       Date:  2015-09-20

Review 9.  Drug-related problems in hospitals: a review of the recent literature.

Authors:  Anita Krähenbühl-Melcher; Raymond Schlienger; Markus Lampert; Manuel Haschke; Jürgen Drewe; Stephan Krähenbühl
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

10.  In-hospital fall-risk screening in 4,735 geriatric patients from the LUCAS project.

Authors:  L Neumann; V S Hoffmann; S Golgert; J Hasford; W Von Renteln-Kruse
Journal:  J Nutr Health Aging       Date:  2013-03       Impact factor: 4.075

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.