Literature DB >> 10715145

4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, valdecoxib: a potent and selective inhibitor of COX-2.

J J Talley1, D L Brown, J S Carter, M J Graneto, C M Koboldt, J L Masferrer, W E Perkins, R S Rogers, A F Shaffer, Y Y Zhang, B S Zweifel, K Seibert.   

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Year:  2000        PMID： 10715145     DOI： 10.1021/jm990577v

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  55 in total

1.  A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin.

Authors:  M Ouellet; D Riendeau; M D Percival
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

Review 2.  COX-2 and cancer: a new approach to an old problem.

Authors:  Y S Bakhle
Journal:  Br J Pharmacol       Date:  2001-11       Impact factor: 8.739

Review 3.  Recent methodologies toward the synthesis of valdecoxib: a potential 3,4-diarylisoxazolyl COX-II inhibitor.

Authors:  Sureshbabu Dadiboyena; Adel Nefzi
Journal:  Eur J Med Chem       Date:  2010-08-06       Impact factor: 6.514

4.  QSAR and classification models of a novel series of COX-2 selective inhibitors: 1,5-diarylimidazoles based on support vector machines.

Authors:  H X Liu; R S Zhang; X J Yao; M C Liu; Z D Hu; B T Fan
Journal:  J Comput Aided Mol Des       Date:  2004-06       Impact factor: 3.686

Review 5.  The second generation of COX-2 inhibitors: what advantages do the newest offer?

Authors:  Dirk O Stichtenoth; Jürgen C Frölich
Journal:  Drugs       Date:  2003       Impact factor: 9.546

Review 6.  Current advances in the synthesis and biological potencies of tri- and tetra-substituted 1H-imidazoles.

Authors:  Majid M Heravi; Mansoureh Daraie; Vahideh Zadsirjan
Journal:  Mol Divers       Date:  2015-04-12       Impact factor: 2.943

7.  Diverse methyl sulfone-containing benzo[b]thiophene library via iodocyclization and palladium-catalyzed coupling.

Authors:  Chul-Hee Cho; Benjamin Neuenswander; Richard C Larock
Journal:  J Comb Chem       Date:  2010-03-08

8.  Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis.

Authors:  Karin Muller-Decker; Gitta Neufang; Irina Berger; Melanie Neumann; Friedrich Marks; Gerhard Furstenberger
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-09       Impact factor: 11.205

9.  Solution phase synthesis of a diverse library of highly substituted isoxazoles.

Authors:  Jesse P Waldo; Saurabh Mehta; Benjamin Neuenswander; Gerald H Lushington; Richard C Larock
Journal:  J Comb Chem       Date:  2008-08-01

10.  4-(4-Nitro-benzene-sulfonamido)pyridinium trichloro-acetate.

Authors:  Peng-Wei Zhang; Wen-Yuan Gao; Li Zhang; Shou-Cheng Pu
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-01-16
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