Literature DB >> 1071439

Study of markers of human erythroid differentiation in hybrid cells.

A Deisseroth, A Nienhuis.   

Abstract

Somatic cell hybrids exhibiting co-expression of the globin genes of two species were generated by fusion of mouse erythroleukemia cells with Chinese hamster or human marrow erythroid cells. In contrast, extinction of the mouse globin genes occurred in hybrids formed between the erythroleukemia cells and human fibroblasts. Direct detection of the human globin genes in human X mouse fibroblast hybrids was achieved by annealing of DNA from these cells to human globin complementary DNA. This method was developed to permit the chromosomal assignment of the human globin genes.

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Year:  1976        PMID： 1071439     DOI： 10.1007/bf02835448

Source DB:  PubMed          Journal:  In Vitro        ISSN： 0073-5655


  33 in total

1.  THE AMINO ACID SEQUENCE OF THE GAMMA CHAIN OF HUMAN FETAL HEMOGLOBIN.

Authors:  W A SCHROEDER; J R SHELTON; J B SHELTON; J CORMICK; R T JONES
Journal:  Biochemistry       Date:  1963 Sep-Oct       Impact factor: 3.162

2.  The fusion of two peptide chains in hemoglobin Lepore and its interpretation as a genetic deletion.

Authors:  C BAGLIONI
Journal:  Proc Natl Acad Sci U S A       Date:  1962-11-15       Impact factor: 11.205

3.  Isolation of hybrid cells that exhibit markers of erythroid differentiation.

Authors:  A Deisseroth
Journal:  N Engl J Med       Date:  1976-01-15       Impact factor: 91.245

4.  Differentiation in erythroleukemic cells and their somatic hybrids.

Authors:  S H Orkin; F I Harosi; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1975-01       Impact factor: 11.205

5.  Multiple alpha chain loci for human haemoglobins: Hb J-Buda and Hb G-Pest.

Authors:  S R Hollán; J G Szelenyi; G Brimhall; M Duerst; R T Jones; R D Koler; Z Stocklen
Journal:  Nature       Date:  1972-01-07       Impact factor: 49.962

6.  In vitro synthesis of DNA complementary to rabbit reticulocyte 10S RNA.

Authors:  I M Verma; G F Temple; H Fan; D Baltimore
Journal:  Nat New Biol       Date:  1972-02-09

7.  Hybrid cells and human genes.

Authors:  F H Ruddle; R S Kucherlapati
Journal:  Sci Am       Date:  1974-07       Impact factor: 2.142

8.  Evidence for a new haemoglobin chain (zeta-chain).

Authors:  G L Capp; D A Rigas; R T Jones
Journal:  Nature       Date:  1970-10-17       Impact factor: 49.962

9.  Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide.

Authors:  C Friend; W Scher; J G Holland; T Sato
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205

10.  A limited number of globin genes in human DNA.

Authors:  R Gambino; D Kacian; J O'Donnell; F Ramirez; P A Marks; A Bank
Journal:  Proc Natl Acad Sci U S A       Date:  1974-10       Impact factor: 11.205
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  2 in total

1.  Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids.

Authors:  A Deisseroth; A Nienhuis; J Lawrence; R Giles; P Turner; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

2.  Comparative mapping using somatic cell hybrids.

Authors:  J D Minna; P A Lalley; U Francke
Journal:  In Vitro       Date:  1976-11
  2 in total

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