Literature DB >> 10712916

Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions.

S H Soderling1, J A Beavo.   

Abstract

The past eighteen months have provided much progress in the cyclic nucleotide phosphodiesterase (PDE) field. Six new phosphodiesterase genes have been discovered and characterized. In addition, several new highly specific PDE inhibitors have been developed and approved for clinical use. Finally, new strategies have been employed to determine PDE function in model systems including the use of antisense oligonucleotide and disruption techniques.

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Year:  2000        PMID： 10712916     DOI： 10.1016/s0955-0674(99)00073-3

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  138 in total

1.  mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module.

Authors:  K L Dodge; S Khouangsathiene; M S Kapiloff; R Mouton; E V Hill; M D Houslay; L K Langeberg; J D Scott
Journal:  EMBO J       Date:  2001-04-17       Impact factor: 11.598

Review 2.  The many dimensions of cAMP signaling.

Authors:  J H Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  2001-11-20       Impact factor: 11.205

3.  KMUP-1 relaxes rabbit corpus cavernosum smooth muscle in vitro and in vivo: involvement of cyclic GMP and K(+) channels.

Authors:  Rong-Jyh Lin; Bin-Nan Wu; Yi-Ching Lo; Kuo-Pyng Shen; Young-Tso Lin; Chun-Hsiung Huang; Ing-Jun Chen
Journal:  Br J Pharmacol       Date:  2002-03       Impact factor: 8.739

4.  Activation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth muscle.

Authors:  K S Murthy
Journal:  Biochem J       Date:  2001-11-15       Impact factor: 3.857

5.  IGF-I-induced differentiation of L6 myogenic cells requires the activity of cAMP-phosphodiesterase.

Authors:  Vania De Arcangelis; Dario Coletti; Marco Conti; Michel Lagarde; Mario Molinaro; Sergio Adamo; Georges Nemoz; Fabio Naro
Journal:  Mol Biol Cell       Date:  2003-04       Impact factor: 4.138

6.  Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension.

Authors:  Fiona Murray; Margaret R MacLean; Nigel J Pyne
Journal:  Br J Pharmacol       Date:  2002-12       Impact factor: 8.739

Review 7.  Photoreceptor guanylate cyclase variants: cGMP production under control.

Authors:  Izabela Sokal; Andrei Alekseev; Krzysztof Palczewski
Journal:  Acta Biochim Pol       Date:  2003       Impact factor: 2.149

8.  Dual effect of diazepam on cGMP levels in rat brain slices.

Authors:  L A M Aerden; H Steinbusch; M Markerink-van Ittersum; J Lodder; J de Vente
Journal:  Neurochem Res       Date:  2004-09       Impact factor: 3.996

9.  Self-renewal and differentiation of mouse embryonic stem cells as measured by Oct4 expression: the role of the cAMP/PKA pathway.

Authors:  S Faherty; A Fitzgerald; M Keohan; L R Quinlan
Journal:  In Vitro Cell Dev Biol Anim       Date:  2007-01       Impact factor: 2.416

10.  Regulation of intracellular cyclic AMP in skeletal muscle cells involves the efflux of cyclic nucleotide to the extracellular compartment.

Authors:  Rosely Oliveira Godinho; Valter Luiz Costa
Journal:  Br J Pharmacol       Date:  2003-03       Impact factor: 8.739
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