| Literature DB >> 10712896 |
Abstract
The fourth transmembrane helix (S4) is the primary voltage-sensor of voltage-gated ion channels. Recent studies have used fluorescence resonance energy transfer as a spectroscopic ruler to determine the nature and magnitude of the voltage-induced movement of S4 that leads to channel opening.Mesh:
Substances:
Year: 2000 PMID: 10712896 DOI: 10.1016/s0960-9822(00)00354-7
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834