| Literature DB >> 10708748 |
I Dan1, N M Watanabe, T Kobayashi, K Yamashita-Suzuki, Y Fukagaya, E Kajikawa, W K Kimura, T M Nakashima, K Matsumoto, J Ninomiya-Tsuji, A Kusumi.
Abstract
A new germinal center kinase (GCK) family kinase, Misshapen/NIKs-related kinase (MINK), has been cloned and its expression has been characterized in several tissues and various developmental stages of the mouse brain. MINK encodes a 1300 amino acid polypeptide, consisting of an N-terminal kinase domain, a proline-rich intermediate region, and a C-terminal GCK homology region. The expression of MINK is up-regulated during the postnatal development of the mouse brain. MINK activates the cJun N-terminal kinase and the p38 pathways.Entities:
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Year: 2000 PMID: 10708748 DOI: 10.1016/s0014-5793(00)01247-3
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124