Literature DB >> 10703062

Screening of the needles of different yew species and cultivars for paclitaxel and related taxoids.

E L van Rozendaal1, G P Lelyveld, T A van Beek.   

Abstract

The needles of several yew species and cultivars were analysed by high-pressure liquid chromatography for paclitaxel, 10-deacetylpaclitaxel, cephalomannine, baccatin III, 10-deacetylbaccatin III and brevifoliol. About 750 samples were collected from five different locations in the Netherlands and the UK. The results of this screening show a large variation in taxane content between the different species and cultivars. The content of paclitaxel and 10-deacetylbaccatin III varied from 0 to 500 micrograms/g and 0 to 4800 micrograms/g dried needles, respectively. Brevifoliol was found in a very high concentration in Taxus brevifolia. 10-Deacetylpaclitaxel, cephalomannine and baccatin III were found in concentrations ranging from 0 to 500 micrograms/g dried needles.

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Year:  2000        PMID: 10703062     DOI: 10.1016/s0031-9422(99)00094-1

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  11 in total

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4.  Seasonal-based temporal changes fluctuate expression patterns of TXS, DBAT, BAPT and DBTNBT genes alongside production of associated taxanes in Taxus baccata.

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5.  A fungal endophyte induces transcription of genes encoding a redundant fungicide pathway in its host plant.

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6.  The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing.

Authors:  Da Cheng Hao; GuangBo Ge; PeiGen Xiao; YanYan Zhang; Ling Yang
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7.  Seasonal Dynamics of Metabolites in Needles of Taxus wallichiana var. mairei.

Authors:  Li Yang; Zan-Sheng Zheng; Fang Cheng; Xiao Ruan; De-An Jiang; Cun-De Pan; Qiang Wang
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8.  Extraction, Purification, and Biological Activities of Polysaccharides from Branches and Leaves of Taxus cuspidata S. et Z.

Authors:  Ping Jiang; Qian Zhang; Yajie Zhao; Jia Xiong; Fei Wang; Ting Zhang; Chenmeng Zhang
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9.  Improving 10-deacetylbaccatin III-10-β-O-acetyltransferase catalytic fitness for Taxol production.

Authors:  Bing-Juan Li; Hao Wang; Ting Gong; Jing-Jing Chen; Tian-Jiao Chen; Jin-Ling Yang; Ping Zhu
Journal:  Nat Commun       Date:  2017-05-18       Impact factor: 14.919

10.  Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas.

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Journal:  BMC Plant Biol       Date:  2018-09-17       Impact factor: 4.215

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