Literature DB >> 10702515

Description of a nonlethal herpes simplex virus type 1 glycoprotein D deletion mutant affecting a site frequently used for PCR.

P V Coyle1, S Jain, D Wyatt, C McCaughey, H J O'Neill.   

Abstract

We report a herpes simplex virus type 1 mutant which failed to amplify with a commonly used glycoprotein D primer set. The virus contained a nine-base deletion in the gene's 5' nontranslated region. The altered amplicon was clearly distinguishable on a 4% high-resolution agarose gel.

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Year:  2000        PMID: 10702515      PMCID: PMC95871          DOI: 10.1128/CDLI.7.2.322-324.2000

Source DB:  PubMed          Journal:  Clin Diagn Lab Immunol        ISSN: 1071-412X


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