OBJECTIVE: The relationship between attention deficit hyperactivity disorder (ADHD) and earlier age at onset of affective illness was examined in probands with a history of bipolar disorder. METHOD: The authors assessed 56 adult bipolar subjects. Those with a history of childhood ADHD (N=8) were age and sex matched with bipolar subjects without a history of childhood ADHD (N=8). RESULTS: The age at onset of the first affective episode was lower for the subjects with bipolar disorder and a history of childhood ADHD (mean=12.1 years, SD=4.6) than for those without a history of childhood ADHD (mean=20. 0 years, SD=11.3). CONCLUSIONS: ADHD in children of bipolar probands might identify children at highest risk for development of bipolar disorder.
OBJECTIVE: The relationship between attention deficit hyperactivity disorder (ADHD) and earlier age at onset of affective illness was examined in probands with a history of bipolar disorder. METHOD: The authors assessed 56 adult bipolar subjects. Those with a history of childhood ADHD (N=8) were age and sex matched with bipolar subjects without a history of childhood ADHD (N=8). RESULTS: The age at onset of the first affective episode was lower for the subjects with bipolar disorder and a history of childhood ADHD (mean=12.1 years, SD=4.6) than for those without a history of childhood ADHD (mean=20. 0 years, SD=11.3). CONCLUSIONS:ADHD in children of bipolar probands might identify children at highest risk for development of bipolar disorder.
Authors: Nikos Makris; Larry J Seidman; Ariel Brown; Eve M Valera; Jonathan R Kaiser; Carter R Petty; Lichen Liang; Megan Aleardi; Denise Boriel; Carly S Henderson; Michelle Giddens; Stephen V Faraone; Thomas J Spencer; Joseph Biederman Journal: Psychiatry Res Date: 2012-05-27 Impact factor: 3.222
Authors: Daniel P Dickstein; Elizabeth C Finger; Martha Skup; Daniel S Pine; James R Blair; Ellen Leibenluft Journal: Bipolar Disord Date: 2010-11 Impact factor: 6.744
Authors: Daniel P Dickstein; Brendan A Rich; Roxann Roberson-Nay; Lisa Berghorst; Deborah Vinton; Daniel S Pine; Ellen Leibenluft Journal: Bipolar Disord Date: 2007-11 Impact factor: 6.744