Literature DB >> 10698458

Design, synthesis and biological evaluation of 7-azatricyclodecanes: analogues of cocaine.

A P Tamiz1, M P Smith, A P Kozikowski.   

Abstract

The synthesis and biological activity of a series of azatricyclodecane analogues of cocaine are described. All compounds studied in this series exhibit nanomolar potency and good selectivity for the serotonin transporter versus the dopamine transporter.

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Year:  2000        PMID: 10698458     DOI: 10.1016/s0960-894x(99)00685-x

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine.

Authors:  Jeffrey S Stehouwer; Mark M Goodman
Journal:  PET Clin       Date:  2009-01

2.  (1R,3R,3aS,8aR)-4-Oxo-3-phenyl-1-[(1R)-1-phenyl-eth-yl]deca-hydro-cyclo-hepta-[b]pyrrol-1-ium bromide.

Authors:  Victor B Rybakov; Dmitry S Belov; Evgeny R Lukyanenko; Alexander V Kurkin; Marina A Yurovskaya
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-06-27
  2 in total

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