Literature DB >> 10697858

A fine balance between oxidised and reduced haem controls the survival of intraerythrocytic plasmodia.

D Taramelli1, D Monti, N Basilico, S Parapini, F Omodeo-Salé, P Olliaro.   

Abstract

The polymerisation of haemoglobin-derived ferri-protoporphyrin IX (Fe(III)PPIX) to haemozoin (malaria pigment) is a crucial process for intraerythrocytic plasmodia to prevent haem toxicity. It is also the target of in-use antimalarial drugs and newer compounds. This reaction and the inhibition thereof can be reproduced and studied in vitro.

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Year:  1999        PMID： 10697858

Source DB:  PubMed          Journal:  Parassitologia        ISSN： 0048-2951


  8 in total

1.  Chemo Suppressive and Curative Potential of Hypoestes forskalei Against Plasmodium berghei: Evidence for in vivo Antimalarial Activity.

Authors:  Desye Misganaw; Gedefaw Getnet Amare; Getnet Mengistu
Journal:  J Exp Pharmacol       Date:  2020-09-07

2.  In vivo antimalarial activity of crude extracts and solvent fractions of leaves of Strychnos mitis in Plasmodium berghei infected mice.

Authors:  Selamawit Fentahun; Eyasu Makonnen; Tesfaye Awas; Mirutse Giday
Journal:  BMC Complement Altern Med       Date:  2017-01-05       Impact factor: 3.659

3.  Antimalarial Activity of Crude Extract and Solvent Fractions of the Leaves of Bersama abyssinica Fresen. (Melianthaceae) against Plasmodium berghei Infection in Swiss Albino Mice.

Authors:  Agumas Alemu Alehegn; Jibril Seid Yesuf; Eshetie Melese Birru
Journal:  Evid Based Complement Alternat Med       Date:  2020-06-09       Impact factor: 2.629

4.  Antimalarial Activity of Cordia africana (Lam.) (Boraginaceae) Leaf Extracts and Solvent Fractions in Plasmodium berghei-Infected Mice.

Authors:  Dawit Zewdu Wondafrash; Dayananda Bhoumik; Birhanetensay Masresha Altaye; Helen Bitew Tareke; Brhane Teklebrhan Assefa
Journal:  Evid Based Complement Alternat Med       Date:  2019-08-18       Impact factor: 2.629

5.  Evaluation of Antimalarial Activity of Methanolic Root Extract of Myrica salicifolia A Rich (Myricaceae) Against Plasmodium berghei-Infected Mice.

Authors:  Zemene Demelash Kifle; Getnet Mequanint Adinew; Mestayet Geta Mengistie; Abyot Endale Gurmu; Engidaw Fentahun Enyew; Bahiru Tenaw Goshu; Gedefaw Getenet Amare
Journal:  J Evid Based Integr Med       Date:  2020 Jan-Dec

6.  Phytochemical analysis and anti-microbial activities of Artemisia spp. and rapid isolation methods of artemisinin.

Authors:  Seid Mohammed; Aman Dekabo; Tilahun Hailu
Journal:  AMB Express       Date:  2022-02-12       Impact factor: 3.298

7.  In vivo assessment of the antimalarial activity and acute oral toxicity of an ethanolic seed extract of Spondias pinnata (L.f.) Kurz.

Authors:  Prapaporn Chaniad; Arisara Phuwajaroanpong; Walaiporn Plirat; Tachpon Techarang; Arnon Chukaew; Chuchard Punsawad
Journal:  BMC Complement Med Ther       Date:  2022-03-16

8.  In Vivo Anti-Malarial Activity of the Aqueous Root Extract of Euclea divinorum Hiern (Ebenaceae) against Plasmodium berghei ANKA.

Authors:  Fentaw Girmaw; Ephrem Engidawork
Journal:  Evid Based Complement Alternat Med       Date:  2022-07-30       Impact factor: 2.650
  8 in total

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