Literature DB >> 10694886

Eukaryotic DNA polymerases, a growing family.

U Hübscher1, H P Nasheuer, J E Syväoja.   

Abstract

In eukaryotic cells, DNA polymerases are required to maintain the integrity of the genome during processes, such as DNA replication, various DNA repair events, translesion DNA synthesis, DNA recombination, and also in regulatory events, such as cell cycle control and DNA damage checkpoint function. In the last two years, the number of known DNA polymerases has increased to at least nine (called alpha, beta, gamma, delta, epsilon, zeta, eta, t and iota), and yeast Saccharomyces cerevisiae contains REV1 deoxycytidyl transferase.

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Year:  2000        PMID: 10694886     DOI: 10.1016/s0968-0004(99)01523-6

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  52 in total

1.  DNA polymerase epsilon is required for coordinated and efficient chromosomal DNA replication in Xenopus egg extracts.

Authors:  S Waga; T Masuda; H Takisawa; A Sugino
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-10       Impact factor: 11.205

2.  The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance.

Authors:  E C Friedberg; W J Feaver; V L Gerlach
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

3.  Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta.

Authors:  F Boudsocq; S Iwai; F Hanaoka; R Woodgate
Journal:  Nucleic Acids Res       Date:  2001-11-15       Impact factor: 16.971

4.  Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase alpha-primase.

Authors:  Christian Melle; Heinz-Peter Nasheuer
Journal:  Nucleic Acids Res       Date:  2002-04-01       Impact factor: 16.971

Review 5.  Alzheimer's disease research enters a "new cycle": how significant?

Authors:  A Copani; M A Sortino; F Nicoletti; Stella A M Giuffrida
Journal:  Neurochem Res       Date:  2002-02       Impact factor: 3.996

6.  Structure and function of the fourth subunit (Dpb4p) of DNA polymerase epsilon in Saccharomyces cerevisiae.

Authors:  T Ohya; S Maki; Y Kawasaki; A Sugino
Journal:  Nucleic Acids Res       Date:  2000-10-15       Impact factor: 16.971

7.  Role of the p68 subunit of human DNA polymerase alpha-primase in simian virus 40 DNA replication.

Authors:  Robert D Ott; Christoph Rehfuess; Vladimir N Podust; Jill E Clark; Ellen Fanning
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

8.  Schizosacchromyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replication.

Authors:  Wenyi Feng; Luis Rodriguez-Menocal; Gökhan Tolun; Gennaro D'Urso
Journal:  Mol Biol Cell       Date:  2003-05-18       Impact factor: 4.138

Review 9.  Divide and die: cell cycle events as triggers of nerve cell death.

Authors:  Karl Herrup; Rachael Neve; Susan L Ackerman; Agata Copani
Journal:  J Neurosci       Date:  2004-10-20       Impact factor: 6.167

10.  E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase epsilon B-subunit gene POLE2.

Authors:  D Huang; M Jokela; J Tuusa; S Skog; K Poikonen; J E Syväoja
Journal:  Nucleic Acids Res       Date:  2001-07-01       Impact factor: 16.971

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