Literature DB >> 10692171

Application of short tandem repeat of genomic DNA and mitochondrial DNA for identification of mixed-up tissue specimens.

K Sano1, K Takayanagi, T Kaneko, C Liu, T Kinoshita, N Nakamura, H Asamura, M Ito, H Fukushima, M Hotchi.   

Abstract

Deoxyribonucleic acid (DNA) typing methods, short tandem repeat of genomic DNA and mitochondrial DNA with the use of polymerase chain reaction amplification, were applied to formalin-fixed, paraffin-embedded tissues submitted for diagnosis, to identify and sort out mixed-up tissue specimens. These techniques were found to be reliable, reproducible and specific for personal identification, and thus to eliminate the need for further examinations and to prevent unnecessary surgery.

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Year:  2000        PMID: 10692171     DOI: 10.1046/j.1440-1827.2000.01010.x

Source DB:  PubMed          Journal:  Pathol Int        ISSN: 1320-5463            Impact factor:   2.534


  1 in total

1.  Mitochondrial DNA haplotyping revealed the presence of mixed up benign and neoplastic tissue sections from two individuals on the same prostatic biopsy slide.

Authors:  A Alonso; C Alves; M P Suárez-Mier; C Albarrán; L Pereira; L Fernández de Simón; P Martín; O García; L Gusmão; M Sancho; A Amorim
Journal:  J Clin Pathol       Date:  2005-01       Impact factor: 3.411

  1 in total

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