Literature DB >> 10691701

Identification of deoxymiroestrol as the actual rejuvenating principle of "Kwao Keur", Pueraria mirifica. The known miroestrol may be an artifact.

S Chansakaow1, T Ishikawa, H Seki, K Sekine (née Yoshizawa), M Okada, C Chaichantipyuth.   

Abstract

Miroestrol (1) has been isolated previously as an active principle from "Kwao Keur" (Pueraria mirifica), a rejuvenating folk medicine from Thailand. Reinvestigation using bioassay-guided purification has resulted in the isolation of a new potent phytoestrogen, deoxymiroestrol (2). The facile aerial oxidation of 2 into 1 suggests the possibility that 1 may be an artifact.

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Year:  2000        PMID： 10691701     DOI： 10.1021/np990547v

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  21 in total

1.  Anti-miroestrol polyclonal antibodies: a comparison of immunogen preparations used to obtain desired antibody properties.

Authors:  Tharita Kitisripanya; Kamonthip Jutathis; Chadathorn Inyai; Jukrapun Komaikul; Orapin Udomsin; Gorawit Yusakul; Hiroyuki Tanaka; Waraporn Putalun
Journal:  J Nat Med       Date:  2015-11-13       Impact factor: 2.343

2.  The estrogenic effect of Pueraria mirifica on gonadotrophin levels in aged monkeys.

Authors:  Hataitip Trisomboon; Suchinda Malaivijitnond; Gen Watanabe; Wichai Cherdshewasart; Kazuyoshi Taya
Journal:  Endocrine       Date:  2006-02       Impact factor: 3.633

3.  Botanical origin of dietary supplements labeled as "Kwao Keur", a folk medicine from Thailand.

Authors:  Takuro Maruyama; Maiko Kawamura; Ruri Kikura-Hanajiri; Yukihiro Goda
Journal:  J Nat Med       Date:  2013-05-16       Impact factor: 2.343

4.  The effects of Pueraria mirifica extract, diadzein and genistein in testosterone-induced prostate hyperplasia in male Sprague Dawley rats.

Authors:  Jamaludin Mohamad; Siti Saleha Masrudin; Zazali Alias; Nur Airina Muhamad
Journal:  Mol Biol Rep       Date:  2019-02-01       Impact factor: 2.316

5.  Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test.

Authors:  Jiranan Chaingam; Tharita Kitisripanya; Supaluk Krittanai; Seiichi Sakamoto; Hiroyuki Tanaka; Waraporn Putalun
Journal:  J Nat Med       Date:  2019-04-11       Impact factor: 2.343

6.  Ovulation block by Pueraria mirifica: a study of its endocrinological effect in female monkeys.

Authors:  Hataitip Trisomboon; Suchinda Malaivijitnond; Gen Watanabe; Kazuyoshi Taya
Journal:  Endocrine       Date:  2005-02       Impact factor: 3.633

7.  Enzyme linked immunosorbent assay for total potent estrogenic miroestrol and deoxymiroestrol of Pueraria candollei, a Thai herb for menopause remedy.

Authors:  Gorawit Yusakul; Tharita Kitisripanya; Thaweesak Juengwatanatrakul; Seiichi Sakamoto; Hiroyuki Tanaka; Waraporn Putalun
Journal:  J Nat Med       Date:  2018-02-28       Impact factor: 2.343

8.  Effects of Pueraria mirifica, an herb containing phytoestrogens, on reproductive organs and fertility of adult male mice.

Authors:  Sukanya Jaroenporn; Suchinda Malaivijitnond; Kingkaew Wattanasirmkit; Hataitip Trisomboon; Gen Watanabe; Kazuyoshi Taya; Wichai Cherdshewasart
Journal:  Endocrine       Date:  2006-08       Impact factor: 3.633

9.  Evaluation of white Kwao Krua (Pueraria candollei Grah. ex Benth.) products sold in Thailand by molecular, chemical, and microscopic analyses.

Authors:  Aekkhaluck Intharuksa; Masashi Kitamura; Nichakan Peerakam; Wannaree Charoensup; Hirokazu Ando; Yohei Sasaki; Panee Sirisa-Ard
Journal:  J Nat Med       Date:  2019-08-03       Impact factor: 2.343

10.  High-content screening and mechanism-based evaluation of estrogenic botanical extracts.

Authors:  Cassia R Overk; Ping Yao; Shaonong Chen; Shixing Deng; Ayano Imai; Matthew Main; Andreas Schinkovitz; Norman R Farnsworth; Guido F Pauli; Judy L Bolton
Journal:  Comb Chem High Throughput Screen       Date:  2008-05       Impact factor: 1.339
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