Literature DB >> 10689758

Statistical modelling of the determinants of historical exposure to bitumen and polycyclic aromatic hydrocarbons among paving workers.

I Burstyn1, H Kromhout, T Kauppinen, P Heikkilä, P Boffetta.   

Abstract

INTRODUCTION: An industrial hygiene database has been constructed for the exposure assessment in a study of cancer risk among asphalt workers. AIM: To create models of bitumen and polycyclic aromatic hydrocarbons (PAH) exposure intensity among paving workers.
METHODS: Individual exposure measurements from pavers (N = 1581) were collected from 8 countries. Correlation patterns between exposure measures were examined and factors affecting exposure were identified using statistical modelling.
RESULTS: Inhalable dust appeared to be a good proxy of bitumen fume exposure. Bitumen fume and vapour levels were not correlated. Benzo(a)pyrene level appeared to be a good indicator of PAH exposure. All exposures steadily declined over the last 20 years. Mastic laying, re-paving, surface dressing, oil gravel paving and asphalt temperature were significant determinants of bitumen exposure. Coal tar use dictated PAH exposure levels. DISCUSSION: Bitumen fume, vapour and PAH have different determinants of exposure. For paving workers, exposure intensity can be assessed on the basis of time period and production characteristics.

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Year:  2000        PMID: 10689758

Source DB:  PubMed          Journal:  Ann Occup Hyg        ISSN: 0003-4878


  21 in total

1.  Design of measurement strategies for workplace exposures.

Authors:  Hans Kromhout
Journal:  Occup Environ Med       Date:  2002-05       Impact factor: 4.402

Review 2.  Occupational exposure assessment in case-control studies: opportunities for improvement.

Authors:  K Teschke; A F Olshan; J L Daniels; A J De Roos; C G Parks; M Schulz; T L Vaughan
Journal:  Occup Environ Med       Date:  2002-09       Impact factor: 4.402

3.  Validity of empirical models of exposure in asphalt paving.

Authors:  I Burstyn; P Boffetta; G A Burr; A Cenni; U Knecht; G Sciarra; H Kromhout
Journal:  Occup Environ Med       Date:  2002-09       Impact factor: 4.402

4.  Statistical modeling of occupational chlorinated solvent exposures for case-control studies using a literature-based database.

Authors:  Misty J Hein; Martha A Waters; Avima M Ruder; Mark R Stenzel; Aaron Blair; Patricia A Stewart
Journal:  Ann Occup Hyg       Date:  2010-04-23

Review 5.  Identification of determinants of exposure: consequences for measurement and control strategies.

Authors:  A Burdorf
Journal:  Occup Environ Med       Date:  2005-05       Impact factor: 4.402

6.  Historical limitations of determinant based exposure groupings in the rubber manufacturing industry.

Authors:  R Vermeulen; H Kromhout
Journal:  Occup Environ Med       Date:  2005-11       Impact factor: 4.402

7.  Evaluating predictors of lead exposure for activities disturbing materials painted with or containing lead using historic published data from U.S. workplaces.

Authors:  Sarah J Locke; Nicole C Deziel; Dong-Hee Koh; Barry I Graubard; Mark P Purdue; Melissa C Friesen
Journal:  Am J Ind Med       Date:  2017-02       Impact factor: 2.214

8.  Biomarker variance component estimation for exposure surrogate selection and toxicokinetic inference.

Authors:  Jon R Sobus; Joachim D Pleil; Michael D McClean; Robert F Herrick; Stephen M Rappaport
Journal:  Toxicol Lett       Date:  2010-09-22       Impact factor: 4.372

9.  Sensitivity of the association between increased lung cancer risk and bitumen fume exposure to the assumptions in the assessment of exposure.

Authors:  Frank de Vocht; Igor Burstyn; Gilles Ferro; Ann Olsson; Mia Hashibe; Hans Kromhout; Paolo Boffetta
Journal:  Int Arch Occup Environ Health       Date:  2008-10-28       Impact factor: 3.015

10.  A case-control study of lung cancer nested in a cohort of European asphalt workers.

Authors:  Ann Olsson; Hans Kromhout; Michela Agostini; Johnni Hansen; Christina Funch Lassen; Christoffer Johansen; Kristina Kjaerheim; Sverre Langård; Isabelle Stücker; Wolfgang Ahrens; Thomas Behrens; Marja-Liisa Lindbohm; Pirjo Heikkilä; Dick Heederik; Lützen Portengen; Judith Shaham; Gilles Ferro; Frank de Vocht; Igor Burstyn; Paolo Boffetta
Journal:  Environ Health Perspect       Date:  2010-06-09       Impact factor: 9.031

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