Literature DB >> 10680811

Genetic analysis of vitamin D related genes in Canadian multiple sclerosis patients. Canadian Collaborative Study Group.

J L Steckley1, D A Dyment, A D Sadovnick, N Risch, C Hayes, G C Ebers.   

Abstract

The objective of this study was to investigate genes involved in the metabolism and function of vitamin D as candidate genes for genetic susceptibility to MS. Restriction fragment length polymorphisms and highly polymorphic microsatellite markers within or very close to the 1,25(OH)2D3 receptor (VDR) [12q14], the vitamin D binding protein (DBP) [4q12], and the 25(OH)D2 1alpha-hydroxylase [12q13] loci were analyzed for linkage or association with MS. We found no evidence for linkage or association of these candidate genes with MS in the Canadian population.

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Year:  2000        PMID： 10680811     DOI： 10.1212/wnl.54.3.729

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  13 in total

Review 1.  The emerging role of vitamin D binding protein in multiple sclerosis.

Authors:  Giulio Disanto; Sreeram V Ramagopalan; Andrea E Para; Lahiru Handunnetthi
Journal:  J Neurol       Date:  2010-11-02       Impact factor: 4.849

2.  Vitamin D Receptor Gene Polymorphism and the Risk of Multiple Sclerosis in South Eastern of Iran.

Authors:  Mehrnaz Narooie-Nejad; Maryam Moossavi; Adam Torkamanzehi; Ali Moghtaderi; Saeedeh Salimi
Journal:  J Mol Neurosci       Date:  2015-02-18       Impact factor: 3.444

3.  Genetic predictors of 25-hydroxyvitamin D levels and risk of multiple sclerosis.

Authors:  Kelly Claire Simon; K L Munger; P Kraft; D J Hunter; P L De Jager; A Ascherio
Journal:  J Neurol       Date:  2011-03-23       Impact factor: 4.849

4.  Vitamin D receptor gene polymorphisms in multiple sclerosis patients in northwest Greece.

Authors:  Chrissa Sioka; Stylianos Papakonstantinou; Sofia Markoula; Foteini Gkartziou; Athanasia Georgiou; Ioannis Georgiou; Sygliti-Henrietta Pelidou; Athanassios P Kyritsis; Andreas Fotopoulos
Journal:  J Negat Results Biomed       Date:  2011-05-05

5.  Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis.

Authors:  K Claire Simon; Kassandra L Munger; Alberto Ascherio
Journal:  Mult Scler       Date:  2009-12-09       Impact factor: 6.312

Review 6.  Association between vitamin D receptor polymorphisms and multiple sclerosis: systematic review and meta-analysis of case-control studies.

Authors:  Kalthoum Tizaoui; Wajih Kaabachi; Agnès Hamzaoui; Kamel Hamzaoui
Journal:  Cell Mol Immunol       Date:  2014-07-07       Impact factor: 11.530

7.  Vitamin D levels in people with multiple sclerosis and community controls in Tasmania, Australia.

Authors:  I A F van der Mei; A-L Ponsonby; T Dwyer; L Blizzard; B V Taylor; T Kilpatrick; H Butzkueven; A J McMichael
Journal:  J Neurol       Date:  2007-04-11       Impact factor: 4.849

8.  Vitamin D receptor polymorphisms and 25-hydroxyvitamin D in a group of Sicilian multiple sclerosis patients.

Authors:  Luisa Agnello; C Scazzone; P Ragonese; G Salemi; B Lo Sasso; R Schillaci; G Musso; C Bellia; M Ciaccio
Journal:  Neurol Sci       Date:  2015-10-27       Impact factor: 3.307

Review 9.  Common variants of the vitamin D binding protein gene and adverse health outcomes.

Authors:  Suneil Malik; Lei Fu; David James Juras; Mohamed Karmali; Betty Y L Wong; Agnes Gozdzik; David E C Cole
Journal:  Crit Rev Clin Lab Sci       Date:  2013-02-22       Impact factor: 6.250

Review 10.  Environmental risk factors for multiple sclerosis: a review with a focus on molecular mechanisms.

Authors:  Cullen O'Gorman; Robyn Lucas; Bruce Taylor
Journal:  Int J Mol Sci       Date:  2012-09-18       Impact factor: 6.208
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