Literature DB >> 10679390

Viral-encoded cyclins.

H Laman1, D J Mann, N C Jones.   

Abstract

D-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.

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Year:  2000        PMID: 10679390     DOI: 10.1016/s0959-437x(99)00045-3

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  12 in total

1.  Crystal structure of a gamma-herpesvirus cyclin-cdk complex.

Authors:  G L Card; P Knowles; H Laman; N Jones; N Q McDonald
Journal:  EMBO J       Date:  2000-06-15       Impact factor: 11.598

Review 2.  Strategies in subversion: de-regulation of the mammalian cell cycle by viral gene products.

Authors:  C Swanton; N Jones
Journal:  Int J Exp Pathol       Date:  2001-02       Impact factor: 1.925

3.  Evidence for CDK-dependent and CDK-independent functions of the murine gammaherpesvirus 68 v-cyclin.

Authors:  Jason W Upton; Samuel H Speck
Journal:  J Virol       Date:  2006-09-27       Impact factor: 5.103

Review 4.  The evolutionary conundrum of pathogen mimicry.

Authors:  Nels C Elde; Harmit S Malik
Journal:  Nat Rev Microbiol       Date:  2009-10-06       Impact factor: 60.633

5.  Cyclin-cyclin-dependent kinase regulatory response is linked to substrate recognition.

Authors:  Maria Emanuela Cuomo; Georgina M Platt; Laurence H Pearl; Sibylle Mittnacht
Journal:  J Biol Chem       Date:  2011-01-13       Impact factor: 5.157

6.  Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

Authors:  Heike Laman; Juan M Funes; Hongtao Ye; Stephen Henderson; Laura Galinanes-Garcia; Eiji Hara; Phillip Knowles; Neil McDonald; Chris Boshoff
Journal:  EMBO J       Date:  2005-08-11       Impact factor: 11.598

7.  Viral cyclin-cyclin-dependent kinase 6 complexes initiate nuclear DNA replication.

Authors:  H Laman; D Coverley; T Krude; R Laskey; N Jones
Journal:  Mol Cell Biol       Date:  2001-01       Impact factor: 4.272

8.  Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest.

Authors:  Annika Järviluoma; Emma S Child; Grzegorz Sarek; Papinya Sirimongkolkasem; Gordon Peters; Päivi M Ojala; David J Mann
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

9.  Regulation of the retinoblastoma proteins by the human herpesviruses.

Authors:  Adam J Hume; Robert F Kalejta
Journal:  Cell Div       Date:  2009-01-15       Impact factor: 5.130

10.  Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis.

Authors:  Sonja Koopal; Johanna H Furuhjelm; Annika Järviluoma; Sari Jäämaa; Pawan Pyakurel; Christel Pussinen; Maria Wirzenius; Peter Biberfeld; Kari Alitalo; Marikki Laiho; Päivi M Ojala
Journal:  PLoS Pathog       Date:  2007-09-07       Impact factor: 6.823

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