Literature DB >> 10675892

Newer agents for hormonal contraception in the male.

J K Amory1, W J Bremner.   

Abstract

Efforts to create a hormonal contraceptive for men use testosterone to suppress the production of pituitary gonadotropins and, hence, spermatogenesis. However, conventional testosterone must be administered by frequent injection, and when given alone, is not 100% effective. Therefore, newer androgens and agents that synergistically suppress gonadotropin production are being studied to create an effective and commercially viable contraceptive.

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Year:  2000        PMID: 10675892     DOI: 10.1016/s1043-2760(99)00224-6

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN: 1043-2760            Impact factor:   12.015


  2 in total

Review 1.  Molecular approaches to contraceptive development.

Authors:  U Natraj
Journal:  J Biosci       Date:  2001-11       Impact factor: 1.826

2.  Smad4 overexpression causes germ cell ablation and leydig cell hyperplasia in transgenic mice.

Authors:  Anita Narula; Signe Kilen; Eva Ma; Jessica Kroeger; Erwin Goldberg; Teresa K Woodruff
Journal:  Am J Pathol       Date:  2002-11       Impact factor: 4.307

  2 in total

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