Literature DB >> 10670829

Chinese green tea lowers cholesterol level through an increase in fecal lipid excretion.

T T Yang1, M W Koo.   

Abstract

Lung Chen Tea, a Chinese green tea, has been found to lower serum and liver cholesterol. In this study, its dose response and mechanisms of action on cholesterol lowering in diet-induced hypercholesterolemic Sprague-Dawley rats were investigated. The activities of three major lipid metabolizing enzymes, 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-Co A) reductase, cholesterol 7alpha-hydroxylase and fatty acid synthase (FAS), as well as fecal excretion of bile acids and cholesterol were examined. Lung Chen Tea administration for eight weeks significantly lowered the serum cholesterol in the 2% and 4% groups. The activities of the three enzymes were not affected by Lung Chen Tea, but the fecal bile acids and cholesterol excretions were significantly increased. These results demonstrated that Lung Chen Tea lowered plasma cholesterol by increasing fecal bile acids and cholesterol excretion. Further investigation is required to evaluate the exact mechanisms of action of Lung Chen Tea.

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Year:  2000        PMID: 10670829     DOI: 10.1016/s0024-3205(99)00607-4

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  25 in total

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Journal:  Food Sci Biotechnol       Date:  2016-06-30       Impact factor: 2.391

2.  Safety Evaluation of Green Tea Polyphenols Consumption in Middle-aged Ovariectomized Rat Model.

Authors:  Chwan-Li Shen; Gordon Brackee; Xiao Song; Michael D Tomison; VelvetLee Finckbone; Kelly T Mitchell; Lili Tang; Ming-Chien Chyu; Dale M Dunn; Jia-Sheng Wang
Journal:  J Food Sci       Date:  2017-07-28       Impact factor: 3.167

3.  A Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of STA-2 (Green Tea Polyphenols) in Patients with Chronic Stable Angina.

Authors:  Tsung-Ming Lee; Min-Ji Charng; Chuen-Den Tseng; Ling-Ping Lai
Journal:  Acta Cardiol Sin       Date:  2016-07       Impact factor: 2.672

4.  Effect of red wine on oxidative stress and hypercholesterolemia induced by feeding a high-cholesterol diet in rat.

Authors:  P Montilla; I Espejo; M C Muñoz; I Bujalance; J R Muñoz-Castañeda; I Túnez
Journal:  J Physiol Biochem       Date:  2004-12       Impact factor: 4.158

5.  Epigallocatechin-3-gallate potently inhibits the in vitro activity of hydroxy-3-methyl-glutaryl-CoA reductase.

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Review 6.  Weight control and prevention of metabolic syndrome by green tea.

Authors:  Sudathip Sae-tan; Kimberly A Grove; Joshua D Lambert
Journal:  Pharmacol Res       Date:  2010-12-28       Impact factor: 7.658

Review 7.  Laboratory, epidemiological, and human intervention studies show that tea (Camellia sinensis) may be useful in the prevention of obesity.

Authors:  Kimberly A Grove; Joshua D Lambert
Journal:  J Nutr       Date:  2010-01-20       Impact factor: 4.798

Review 8.  Flavonoids for reduction of atherosclerotic risk.

Authors:  David J Maron
Journal:  Curr Atheroscler Rep       Date:  2004-01       Impact factor: 5.113

9.  GCG-rich tea catechins are effective in lowering cholesterol and triglyceride concentrations in hyperlipidemic rats.

Authors:  Sang Min Lee; Chae Wook Kim; Jung Kee Kim; Hyun Jung Shin; Joo Hyun Baik
Journal:  Lipids       Date:  2008-03-26       Impact factor: 1.880

10.  Absorption of dietary cholesterol oxidation products and their downstream metabolic effects are reduced by dietary apple polyphenols.

Authors:  Yamato Ogino; Kyoichi Osada; Shingo Nakamura; Yutaka Ohta; Tomomasa Kanda; Michihiro Sugano
Journal:  Lipids       Date:  2007-02-10       Impact factor: 1.880

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