Literature DB >> 1066148

Acquired resistance to daunorubicin in a patient with acute myelogenous leukaemia.

B J Smith, D Kundu.   

Abstract

Measurement of in vitro and in vivo resistance to daunorubicin in AML patients suggests that there is no simple correlation between the two. In a patient who became clinically resistant and whose cells showed a parallel increased resistance in vitro we found the acquisition of multiple drug resistance. The increased in vitro resistance to daunorubicin could to some extent be overcome by conjugating daunorubicin to DNA.

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Year:  1976        PMID： 1066148      PMCID： PMC2025136          DOI： 10.1038/bjc.1976.121

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  7 in total

Review 1.  Acute leukemia in adults.

Authors:  M E Beard; G H Fairley
Journal:  Semin Hematol       Date:  1974-01       Impact factor: 3.851

2.  Factors influencing microculture in leukaemia cells.

Authors:  F Balkwill; A Pindar; D Crowther
Journal:  Nature       Date:  1974-10-25       Impact factor: 49.962

3.  Management of adult acute myelogenous leukaemia.

Authors:  D Crowther; R L Powles; C J Bateman; M E Beard; C L Gauci; P F Wrigley; J S Malpas; G H Fairley; R B Scott
Journal:  Br Med J       Date:  1973-01-20

4.  Letter: DNA-daunorubicin complex: preliminary trials in human leukaemia.

Authors:  G Sokal; A Trouet; J L Michaux; G Cornu
Journal:  Eur J Cancer       Date:  1973-05       Impact factor: 9.162

5.  Inhibition of DNA and RNA synthesis by daunorubicin in sensitive and resistant Ehrlich ascites tumor cells in vitro.

Authors:  K Dano; S Frederiksen; P Hellung-Larsen
Journal:  Cancer Res       Date:  1972-06       Impact factor: 12.701

6.  Leukapheresis by continuous flow centrifugation (CFC) in patients with chronic myelocytic leukemia (CML).

Authors:  D Buckner; R G Graw; R J Eisel; E S Henderson; S Perry
Journal:  Blood       Date:  1969-02       Impact factor: 22.113

7.  Diagnostic and prognostic significance of peripheral blood cultural characteristics in adult acute leukaemia.

Authors:  F R Balkwill; R T Oliver
Journal:  Br J Cancer       Date:  1976-04       Impact factor: 7.640
  7 in total
  2 in total

1.  Lack of cross-resistance of a doxorubicin-resistant B16 melanoma line with 4'-deoxy-4'-iodo-doxorubicin.

Authors:  R Supino; M Mariani; E Prosperi; G Parmiani
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

2.  Reversal of natural resistance to bouvardin (NSC 259968) in sarcoma 180 cells in vitro and in vivo by verapamil.

Authors:  M P Chitnis; R S Menon; V S Basrur; M K Adwankar; K Satyamoorthy
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553
  2 in total

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