Literature DB >> 1063591

Diagnostic and prognostic significance of peripheral blood cultural characteristics in adult acute leukaemia.

F R Balkwill, R T Oliver.   

Abstract

A simple liquid culture technique has been used to study peripheral blood from patients with acute myelogenous leukaemia. Evidence is presented that cells from morphologically identical types of leukaemia have differing capacity for "differentiation" from free floating blast cells into plastic-adherent phagocytic, trypsin-resistant macrophage-like cells with Fc and C3 receptors. Preliminary analysis suggests that patients whose cells have the greatest capacity for "differentiation" have a better chance of achieving complete remission.

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Year:  1976        PMID: 1063591      PMCID: PMC2025083          DOI: 10.1038/bjc.1976.65

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  25 in total

1.  Serum agar cultures of blood and bone marrow cells.

Authors:  H J WOODLIFF
Journal:  Acta Haematol       Date:  1961-05       Impact factor: 2.195

2.  Methods developed for culture of human leukocytes.

Authors:  E E OSGOOD; J H BROOKE
Journal:  Methods Med Res       Date:  1958

3.  Macrophage content of tumours in relation to metastatic spread and host immune reaction.

Authors:  S A Eccles; P Alexander
Journal:  Nature       Date:  1974-08-23       Impact factor: 49.962

4.  The growth of mouse bone marrow cells in vitro.

Authors:  T R Bradley; D Metcalf
Journal:  Aust J Exp Biol Med Sci       Date:  1966-06

5.  Primary immune response in cultures of spleen cells.

Authors:  J Marbrook
Journal:  Lancet       Date:  1967-12-16       Impact factor: 79.321

6.  Growth of leukemic cells in culture.

Authors:  M T Aye; J E Till; E A McCulloch
Journal:  Blood       Date:  1972-12       Impact factor: 22.113

7.  Colony formation by normal and leukemic human marrow cells in culture: effect of conditioned medium from human leukocytes.

Authors:  N N Iscove; J S Senn; J E Till; E A McCulloch
Journal:  Blood       Date:  1971-01       Impact factor: 22.113

8.  Growth of human bone marrow in liquid culture.

Authors:  D W Golde; M J Cline
Journal:  Blood       Date:  1973-01       Impact factor: 22.113

9.  The origin and role of blood-borne monocytes in rats with a transplanted myelogenous leukaemia.

Authors:  C L Gauci; A Wrathmell; P Alexander
Journal:  Cancer Lett       Date:  1975-09       Impact factor: 8.679

Review 10.  Human leukaemia: recent tissue culture studies on the nature of myeloid leukaemia.

Authors:  D Metcalf
Journal:  Br J Cancer       Date:  1973-03       Impact factor: 7.640

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  5 in total

1.  Maturation and proliferation capacity of blood cells from untreated acute myeloid leukemia and its prognostic significance.

Authors:  K M Koeppen; I T Boll
Journal:  Klin Wochenschr       Date:  1978-08-01

2.  Growth of acute myeloid leukaemia as discrete subcutaneous tumours in immune-deprived mice.

Authors:  C R Franks; D Bishop; F R Balkwill; R T Oliver; W G Spector
Journal:  Br J Cancer       Date:  1977-05       Impact factor: 7.640

3.  Spontaneous regression of human acute myeloid leukaemia xenografts and phenotypic evidence for maturation.

Authors:  G Palú; P Selby; R Powles; P Alexander
Journal:  Br J Cancer       Date:  1979-11       Impact factor: 7.640

4.  Acquired resistance to daunorubicin in a patient with acute myelogenous leukaemia.

Authors:  B J Smith; D Kundu
Journal:  Br J Cancer       Date:  1976-07       Impact factor: 7.640

5.  Patterns of maturation in short-term culture of human acute myeloid leukaemic cells.

Authors:  G Palú; R Powles; P Selby; B M Summersgill; P Alexander
Journal:  Br J Cancer       Date:  1979-11       Impact factor: 7.640

  5 in total

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