| Literature DB >> 1063591 |
Abstract
A simple liquid culture technique has been used to study peripheral blood from patients with acute myelogenous leukaemia. Evidence is presented that cells from morphologically identical types of leukaemia have differing capacity for "differentiation" from free floating blast cells into plastic-adherent phagocytic, trypsin-resistant macrophage-like cells with Fc and C3 receptors. Preliminary analysis suggests that patients whose cells have the greatest capacity for "differentiation" have a better chance of achieving complete remission.Entities:
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Year: 1976 PMID: 1063591 PMCID: PMC2025083 DOI: 10.1038/bjc.1976.65
Source DB: PubMed Journal: Br J Cancer ISSN: 0007-0920 Impact factor: 7.640