Literature DB >> 10656649

Rhinoscintigraphy: a simple radioisotope technique to study the mucociliary system.

D Di Giuda1, J Galli, M L Calcagni, L Corina, G Paludetti, F Ottaviani, G De Rossi.   

Abstract

PURPOSE: This was a radioisotope study of nasal mucociliary clearance of total and subtotal nasal obstruction.
METHODS: Rhinoscintigraphy was performed by insufflating 1.85 MBq (69 mCi) Tc-99m MAA in 20 patients. Six cases were regarded as the control group, because the presence of small spurs does not affect nasal patency. The remaining 14 patients had various rhinopathic conditions. Two regions of interest were selected, one in the nasal cavity and one in the pharynx. Mucociliary transport speed was calculated.
RESULTS: This parameter appeared to be a sensitive index for the assessment of the degree of mucociliary alteration. It showed that polyposis impairs mucociliary transport most severely, thus confirming the results of other published studies.
CONCLUSIONS: Rhinoscintigraphy proved to be a reliable, easily reproducible, and harmless method, so it may be used for follow-up examinations in patients who have had surgery of the nose and paranasal sinuses, and for drug therapy of rhinopathic conditions.

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Year:  2000        PMID: 10656649     DOI: 10.1097/00003072-200002000-00010

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  11 in total

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3.  Evaluation of nasal mucociliary clearance time in patients with Vitamin-D deficiency.

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4.  How does parental smoking affect nasal mucociliary clearance in children?

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5.  Evaluation of nasal mucociliary activity in patients with chronic renal failure.

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7.  The effect of radiotherapy on mucociliary clearance in patients with laryngeal and nasopharyngeal cancer.

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8.  Physiology and pathophysiology of respiratory mucosa of the nose and the paranasal sinuses.

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9.  Evaluation of Nasal Mucociliary Transport Rate byTc-Macroaggregated Albumin Rhinoscintigraphy in Woodworkers.

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10.  Effects of rapid maxillary expansion or alternating rapid maxillary expansion and constriction on nasal mucociliary clearance : A randomized clinical trial.

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