| Literature DB >> 10650083 |
K D Wellington1, R C Cambie, P S Rutledge, P R Bergquist.
Abstract
Seven new compounds (1-6 and 10) with a unique carbon skeleton have been isolated from the sponge Hamigera tarangaensis, and the structure of a previously reported metabolite has been revised from 12 to 8. The structures have been assigned from extensive NMR examination. Compounds 3-6 showed moderate in-vitro cytotoxicity against P-388, while 3 showed 100% in-vitro virus inhibition against both the Herpes and Polio viruses, with only slight cytotoxicity.Entities:
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Year: 2000 PMID： 10650083 DOI： 10.1021/np9903494
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050