M G Stabin1, M W Konijnenberg. 1. Departamento de Energia Nuclear, Universidade Federal de Pernambuco, Recife, Brazil.
Abstract
UNLABELLED: Absorbed fractions for unit density spheres in an infinite unit density medium, previously calculated for photon emitters and electron emitters, were reevaluated with the Monte Carlo codes EGS4 and MCNP4B. METHODS: Activity was assumed to be distributed uniformly throughout the spheres, and absorbed fractions for self-irradiation were calculated at discrete photon and electron energies. RESULTS: For electrons, the codes were in very good agreement with each other (+/-5%) and with published values, except at higher energies in the very smallest spheres, where some differences exceeded 10%. For photons, the codes were again in good agreement with each other but produced results that varied considerably from published MIRD values. For energies <1 MeV and sphere sizes <50 g, the absorbed fractions determined using the Monte Carlo codes were typically 20%-40% higher than values in MIRD 3 and 8. For energies >1 MeV, the Monte Carlo values were sometimes lower than those in the MIRD documents. Recommended values, generally the average results from the 2 Monte Carlo codes, are given for all sphere sizes and energies for both electrons and photons. CONCLUSION: The absorbed fractions calculated using the Monte Carlo codes should replace the older values and are helpful in evaluating tumor doses, doses to small organs, and other situations in which a uniform distribution of activity throughout a spherical structure of unit density can be assumed.
UNLABELLED: Absorbed fractions for unit density spheres in an infinite unit density medium, previously calculated for photon emitters and electron emitters, were reevaluated with the Monte Carlo codes EGS4 and MCNP4B. METHODS: Activity was assumed to be distributed uniformly throughout the spheres, and absorbed fractions for self-irradiation were calculated at discrete photon and electron energies. RESULTS: For electrons, the codes were in very good agreement with each other (+/-5%) and with published values, except at higher energies in the very smallest spheres, where some differences exceeded 10%. For photons, the codes were again in good agreement with each other but produced results that varied considerably from published MIRD values. For energies <1 MeV and sphere sizes <50 g, the absorbed fractions determined using the Monte Carlo codes were typically 20%-40% higher than values in MIRD 3 and 8. For energies >1 MeV, the Monte Carlo values were sometimes lower than those in the MIRD documents. Recommended values, generally the average results from the 2 Monte Carlo codes, are given for all sphere sizes and energies for both electrons and photons. CONCLUSION: The absorbed fractions calculated using the Monte Carlo codes should replace the older values and are helpful in evaluating tumor doses, doses to small organs, and other situations in which a uniform distribution of activity throughout a spherical structure of unit density can be assumed.
Authors: David M Howard; Kimberlee J Kearfott; Scott J Wilderman; Yuni K Dewaraja Journal: Cancer Biother Radiopharm Date: 2011-09-22 Impact factor: 3.099
Authors: Renaud Lhommel; Larry van Elmbt; Pierre Goffette; Marc Van den Eynde; François Jamar; Stanislas Pauwels; Stephan Walrand Journal: Eur J Nucl Med Mol Imaging Date: 2010-04-27 Impact factor: 9.236
Authors: Phillip G Claringbold; Paul A Brayshaw; Richard A Price; J Harvey Turner Journal: Eur J Nucl Med Mol Imaging Date: 2010-10-30 Impact factor: 9.236
Authors: Jens Kurth; Bernd Joachim Krause; Sarah M Schwarzenböck; Carina Bergner; Oliver W Hakenberg; Martin Heuschkel Journal: Eur J Nucl Med Mol Imaging Date: 2019-09-03 Impact factor: 9.236
Authors: Astrid Capello; Eric Krenning; Bert Bernard; Jean-Claude Reubi; Wout Breeman; Marion de Jong Journal: Eur J Nucl Med Mol Imaging Date: 2005-07-15 Impact factor: 9.236
Authors: Michael G Stabin; X George Xu; Mary A Emmons; W Paul Segars; Chengyu Shi; Michael J Fernald Journal: J Nucl Med Date: 2012-09-11 Impact factor: 10.057
Authors: Marleen Melis; Magda Bijster; Monique de Visser; Mark W Konijnenberg; Jan de Swart; Edgar J Rolleman; Otto C Boerman; Eric P Krenning; Marion de Jong Journal: Eur J Nucl Med Mol Imaging Date: 2009-12 Impact factor: 9.236