Literature DB >> 10646556

Agglutinating activity of alcohol-soluble proteins from quinoa seed flour in celiac disease.

M De Vincenzi1, M Silano, R Luchetti, B Carratù, C Boniglia, N E Pogna.   

Abstract

The edible seeds of the quinoa plant contain small quantities of alcohol-soluble protein which, after peptic-tryptic digestion, are unable to agglutinate K562(s) cells. When separated by affinity chromatography on sepharose-6B coupled with mannan, peptic-tryptic digest separated in two fractions. Fraction B peptides (about 1% of total protein) were shown to agglutinate K562(s) cells at a very low concentration, whereas peptides in fraction A and in the mixed fraction A+B were inactive, suggesting that fraction A contains protective peptides that interfere with the agglutinating activity of toxic peptides in fraction B.

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Year:  1999        PMID： 10646556     DOI： 10.1023/a:1008059519025

Source DB:  PubMed          Journal:  Plant Foods Hum Nutr        ISSN： 0921-9668            Impact factor:   3.921


  11 in total

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Authors:  J H Skerritt; A S Hill
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2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Mannan and oligomers of N-acetylglucosamine protect intestinal mucosa of celiac patients with active disease from in vitro toxicity of gliadin peptides.

Authors:  S Auricchio; G De Ritis; M De Vincenzi; G Magazzù; L Maiuri; E Mancini; M Minetti; O Sapora; V Silano
Journal:  Gastroenterology       Date:  1990-10       Impact factor: 22.682

4.  Oats and barley toxicity in coeliac patients.

Authors:  P G Baker; A E Read
Journal:  Postgrad Med J       Date:  1976-05       Impact factor: 2.401

5.  Prevention by mannan and other sugars of in vitro damage of rat fetal small intestine induced by cereal prolamin peptides toxic for human celiac intestine.

Authors:  S Auricchio; G De Ritis; M De Vincenzi; F Latte; L Maiuri; A Pino; V Raia; V Silano
Journal:  Pediatr Res       Date:  1987-12       Impact factor: 3.756

6.  A new reaction for colorimetric determination of carbohydrates.

Authors:  M Lever
Journal:  Anal Biochem       Date:  1972-05       Impact factor: 3.365

7.  Amines protect in vitro the celiac small intestine from the damaging activity of gliadin peptides.

Authors:  S Auricchio; G De Ritis; M De Vincenzi; V Gentile; L Maiuri; E Mancini; R Porta; V Raia
Journal:  Gastroenterology       Date:  1990-12       Impact factor: 22.682

8.  Coeliac disease. IV. An investigation into the injurious constituents of wheat in connection with their action on patients with coeliac disease.

Authors:  J H VAN DE KAMER; H A WEIJERS; W K DICKE
Journal:  Acta Paediatr       Date:  1953-05       Impact factor: 2.299

9.  Toxicity of wheat flour proteins and protein-derived peptides for in vitro developing intestine from rat fetus.

Authors:  G De Ritis; P Occorsio; S Auricchio; F Gramenzi; G Morisi; V Silano
Journal:  Pediatr Res       Date:  1979-11       Impact factor: 3.756

10.  Agglutinating activity of wheat gliadin peptide fractions in coeliac disease.

Authors:  M De Vincenzi; M R Dessi; C Giovannini; F Maialetti; E Mancini
Journal:  Toxicology       Date:  1995-01-19       Impact factor: 4.221
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  2 in total

1.  Maize prolamins resistant to peptic-tryptic digestion maintain immune-recognition by IgA from some celiac disease patients.

Authors:  Francisco Cabrera-Chávez; Stefania Iametti; Matteo Miriani; Ana M Calderón de la Barca; Gianfranco Mamone; Francesco Bonomi
Journal:  Plant Foods Hum Nutr       Date:  2012-03       Impact factor: 3.921

Review 2.  The gluten-free diet: testing alternative cereals tolerated by celiac patients.

Authors:  Isabel Comino; María de Lourdes Moreno; Ana Real; Alfonso Rodríguez-Herrera; Francisco Barro; Carolina Sousa
Journal:  Nutrients       Date:  2013-10-23       Impact factor: 5.717
  2 in total

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