Literature DB >> 10633002

The proteolytic environment of chronic wounds.

D R Yager1, B C Nwomeh.   

Abstract

A consistent feature of chronic leg and pressure ulcers is chronic inflammation associated with an elevated infiltration of neutrophils. Neutrophils and their proteases have been implicated in mediating the tissue damage associated with a variety of chronic inflammatory diseases. This review discusses our current understanding of the proteolytic enzymes found in chronic wounds and attempts to relate this information to the abundant presence of neutrophils. In addition, the implications that the proteolytic environment may have for current and future treatment strategies of chronic nonhealing wounds are discussed.

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Year:  1999        PMID： 10633002     DOI： 10.1046/j.1524-475x.1999.00433.x

Source DB:  PubMed          Journal:  Wound Repair Regen        ISSN： 1067-1927            Impact factor:   3.617


  61 in total

1.  Comparison of bacteria and fungus-binding mesh, foam and gauze as fillers in negative pressure wound therapy--pressure transduction, wound edge contraction, microvascular blood flow and fluid retention.

Authors:  Malin Malmsjö; Richard Ingemansson; Sandra Lindstedt; Lotta Gustafsson
Journal:  Int Wound J       Date:  2012-06-21       Impact factor: 3.315

Review 2.  Clinical and Antibiofilm Efficacy of Antimicrobial Hydrogels.

Authors:  Simon Finnegan; Steven L Percival
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-07-01       Impact factor: 4.730

3.  Combination Growth Factor Therapy via Electrostatically Assembled Wound Dressings Improves Diabetic Ulcer Healing In Vivo.

Authors:  Benjamin D Almquist; Steven A Castleberry; Julia B Sun; Alice Y Lu; Paula T Hammond
Journal:  Adv Healthc Mater       Date:  2015-08-13       Impact factor: 9.933

Review 4.  Topical negative pressure therapy: mechanisms and indications.

Authors:  Paul E Banwell; Melinda Musgrave
Journal:  Int Wound J       Date:  2004-06       Impact factor: 3.315

5.  Superabsorbent polymer-containing wound dressings have a beneficial effect on wound healing by reducing PMN elastase concentration and inhibiting microbial growth.

Authors:  C Wiegand; M Abel; P Ruth; U C Hipler
Journal:  J Mater Sci Mater Med       Date:  2011-08-26       Impact factor: 3.896

6.  A Formidable Foe Is Sabotaging Your Results: What You Should Know about Biofilms and Wound Healing.

Authors:  Jenny C Barker; Ibrahim Khansa; Gayle M Gordillo
Journal:  Plast Reconstr Surg       Date:  2017-05       Impact factor: 4.730

7.  Alginate membranes loaded with hyaluronic acid and silver nanoparticles to foster tissue healing and to control bacterial contamination of non-healing wounds.

Authors:  Lorena Tarusha; Sergio Paoletti; Andrea Travan; Eleonora Marsich
Journal:  J Mater Sci Mater Med       Date:  2018-02-02       Impact factor: 3.896

8.  The Effect of pH on the Antimicrobial Efficiency of Silver Alginate on Chronic Wound Isolates.

Authors:  Will Slone; Sara Linton; Tyler Okel; Linda Corum; John G Thomas; Steven L Percival
Journal:  J Am Col Certif Wound Spec       Date:  2011-01-31

9.  Manuka honey modulates the release profile of a dHL-60 neutrophil model under anti-inflammatory stimulation.

Authors:  Benjamin A Minden-Birkenmaier; Meghan B Meadows; Kasyap Cherukuri; Matthew P Smeltzer; Richard A Smith; Marko Z Radic; Gary L Bowlin
Journal:  J Tissue Viability       Date:  2020-03-26       Impact factor: 2.932

10.  A pilot study evaluating protein abundance in pressure ulcer fluid from people with and without spinal cord injury.

Authors:  Laura E Edsberg; Jennifer T Wyffels; Rajna Ogrin; B Catharine Craven; Pamela Houghton
Journal:  J Spinal Cord Med       Date:  2014-06-26       Impact factor: 1.985
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