Literature DB >> 10631508

The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases.

D E Cane1, C T Walsh.   

Abstract

Polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs) catalyze chain elongation from simple building blocks to create a diverse array of natural products. PKS and NRPS proteins share striking architectural and organizational similarities that can be exploited to generate entirely new natural products.

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Year:  1999        PMID： 10631508     DOI： 10.1016/s1074-5521(00)80001-0

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  72 in total

1.  Active-site residue, domain and module swaps in modular polyketide synthases.

Authors:  Francesca Del Vecchio; Hrvoje Petkovic; Steven G Kendrew; Lindsey Low; Barrie Wilkinson; Rachel Lill; Jesús Cortés; Brian A M Rudd; Jim Staunton; Peter F Leadlay
Journal:  J Ind Microbiol Biotechnol       Date:  2003-06-14       Impact factor: 3.346

2.  NRPS-PKS: a knowledge-based resource for analysis of NRPS/PKS megasynthases.

Authors:  Mohd Zeeshan Ansari; Gitanjali Yadav; Rajesh S Gokhale; Debasisa Mohanty
Journal:  Nucleic Acids Res       Date:  2004-07-01       Impact factor: 16.971

Review 3.  The ubiquitin/26S proteasome system in plant-pathogen interactions: a never-ending hide-and-seek game.

Authors:  Anne-Sophie Dielen; Saloua Badaoui; Thierry Candresse; Sylvie German-Retana
Journal:  Mol Plant Pathol       Date:  2010-03       Impact factor: 5.663

4.  Distribution and diversity of natural product genes in marine and freshwater cyanobacterial cultures and genomes.

Authors:  Ian M Ehrenreich; John B Waterbury; Eric A Webb
Journal:  Appl Environ Microbiol       Date:  2005-11       Impact factor: 4.792

5.  Probing intra- versus interchain kinetic preferences of L-Thr acylation on dimeric VibF with mass spectrometry.

Authors:  Leslie M Hicks; Carl J Balibar; Christopher T Walsh; Neil L Kelleher; Nathan J Hillson
Journal:  Biophys J       Date:  2006-06-30       Impact factor: 4.033

6.  Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides.

Authors:  Martin Hahn; Torsten Stachelhaus
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-03       Impact factor: 11.205

7.  Biomimetic catalysis of diketopiperazine and dipeptide syntheses.

Authors:  Zheng-Zheng Huang; Luke J Leman; M Reza Ghadiri
Journal:  Angew Chem Int Ed Engl       Date:  2008       Impact factor: 15.336

8.  Type II thioesterase ScoT, associated with Streptomyces coelicolor A3(2) modular polyketide synthase Cpk, hydrolyzes acyl residues and has a preference for propionate.

Authors:  Magdalena Kotowska; Krzysztof Pawlik; Aleksandra Smulczyk-Krawczyszyn; Hubert Bartosz-Bechowski; Katarzyna Kuczek
Journal:  Appl Environ Microbiol       Date:  2008-12-12       Impact factor: 4.792

9.  Involvement of both PKS and NRPS in antibacterial activity in Lysobacter enzymogenes OH11.

Authors:  Juan Zhang; Liangcheng Du; Fengquan Liu; Feifei Xu; Baishi Hu; Vittorio Venturi; Guoliang Qian
Journal:  FEMS Microbiol Lett       Date:  2014-06-03       Impact factor: 2.742

Review 10.  Structural analysis of protein-protein interactions in type I polyketide synthases.

Authors:  Wei Xu; Kangjian Qiao; Yi Tang
Journal:  Crit Rev Biochem Mol Biol       Date:  2012-12-19       Impact factor: 8.250
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