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Literature DB >> 106304

Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments.

H Sakano, J H Rogers, K Hüppi, C Brack, A Traunecker, R Maki, R Wall, S Tonegawa.

Abstract

A 6.8-kilobase DNA fragment containing the sequence coding for the constant region of the mouse immunoglobulin gamma1 heavy chain was cloned from total cellular DNA. Electron microscopic and nucleotide sequencing studies showed that the three protein domains and the hinge region are encoded in separate DNA segments.

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Year: 1979 PMID： 106304 DOI： 10.1038/277627a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

96 in total

1. Cloned pairs of variable region genes for immunoglobulin heavy chains isolated from a clone library of the entire mouse genome.

Authors: D J Kemp; S Cory; J M Adams
Journal: Proc Natl Acad Sci U S A Date: 1979-09 Impact factor: 11.205

2. Sequence analysis of cloned cDNA encoding part of an immunoglobulin heavy chain.

Authors: J Rogers; P Clarke; W Salser
Journal: Nucleic Acids Res Date: 1979-07-25 Impact factor: 16.971

3. Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

Authors: E E Max; J G Seidman; P Leder
Journal: Proc Natl Acad Sci U S A Date: 1979-07 Impact factor: 11.205

4. Some sequence similarities among cloned mouse DNA segments that code for lambda and kappa light chains of immunoglobulins.

Authors: T T Wu; E A Kabat; H Bilofsky
Journal: Proc Natl Acad Sci U S A Date: 1979-09 Impact factor: 11.205

Review 5. Contributions of microbiology to eucaryotic cell biology: new directions for microbiology.

Authors: R Dulbecco
Journal: Microbiol Rev Date: 1979-12

6. Identification of IgF, a hinge-region-containing Ig class, and IgD in Xenopus tropicalis.

Authors: Yaofeng Zhao; Qiang Pan-Hammarström; Shuyang Yu; Nancy Wertz; Xiaofeng Zhang; Ning Li; John E Butler; Lennart Hammarström
Journal: Proc Natl Acad Sci U S A Date: 2006-07-28 Impact factor: 11.205

7. Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene.

Authors: M Raymond; P Gros
Journal: Proc Natl Acad Sci U S A Date: 1989-09 Impact factor: 11.205