Literature DB >> 10624879

Studies on antidiarrhoeal activity of Punica granatum seed extract in rats.

A K Das1, S C Mandal, S K Banerjee, S Sinha, J Das, B P Saha, M Pal.   

Abstract

Methanol extract of Punica granatum seed was evaluated for antidiarrhoeal activity against different experimental models of diarrhoea in rats. P. granatum seed extract treated animals showed significant inhibitory activity against castrol-oil induced diarrhoea and PGE2 induced enteropooling in rats. The extract also showed a significant reduction in gastro-intestinal motility in charcoal meal test in rats. The results obtained established the efficacy of P. granatum seed extract as an antidiarrhoeal agent.

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Year:  1999        PMID： 10624879     DOI： 10.1016/s0378-8741(99)00102-6

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  11 in total

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