Literature DB >> 10623766

Uneven distribution of hepatitis C virus quasispecies in tissues from subjects with end-stage liver disease: confounding effect of viral adsorption and mounting evidence for the presence of low-level extrahepatic replication.

T Laskus1, M Radkowski, L F Wang, M Nowicki, J Rakela.   

Abstract

We have found differences among the populations of hepatitis C virus sequences in serum, peripheral blood mononuclear cells (PBMCs), and various tissues in patients with chronic hepatitis C. These results are compatible with the existence of independent viral compartments in the infected host. Our results also suggest that PBMCs, and probably various tissues, can selectively adsorb viral subpopulations differing in the E2 region.

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Year:  2000        PMID： 10623766      PMCID： PMC111624          DOI： 10.1128/jvi.74.2.1014-1017.2000

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  Dynamic behavior of hepatitis C virus in chronically infected patients receiving liver graft from infected donors.

Authors:  T Laskus; L F Wang; J Rakela; H Vargas; A D Pinna; A C Tsamandas; A J Demetris; J Fung
Journal:  Virology       Date:  1996-06-01       Impact factor: 3.616

2.  Low level or absent in vivo replication of hepatitis C virus and hepatitis G virus/GB virus C in peripheral blood mononuclear cells.

Authors:  J Mellor; G Haydon; C Blair; W Livingstone; P Simmonds
Journal:  J Gen Virol       Date:  1998-04       Impact factor: 3.891

3.  Demonstration of in vitro infection of chimpanzee hepatocytes with hepatitis C virus using strand-specific RT/PCR.

Authors:  R E Lanford; C Sureau; J R Jacob; R White; T R Fuerst
Journal:  Virology       Date:  1994-08-01       Impact factor: 3.616

4.  Distinct HIV-1 long terminal repeat quasispecies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient.

Authors:  M Ait-Khaled; J E McLaughlin; M A Johnson; V C Emery
Journal:  AIDS       Date:  1995-07       Impact factor: 4.177

5.  Search for hepatitis C virus extrahepatic replication sites in patients with acquired immunodeficiency syndrome: specific detection of negative-strand viral RNA in various tissues.

Authors:  T Laskus; M Radkowski; L F Wang; H Vargas; J Rakela
Journal:  Hepatology       Date:  1998-11       Impact factor: 17.425

6.  Hepatitis C virus quasispecies in patients infected with HIV-1: correlation with extrahepatic viral replication.

Authors:  T Laskus; M Radkowski; L F Wang; S J Jang; H Vargas; J Rakela
Journal:  Virology       Date:  1998-08-15       Impact factor: 3.616

7.  Detection of replicative form of hepatitis C virus RNA in peripheral blood mononuclear cells.

Authors:  J T Wang; J C Sheu; J T Lin; T H Wang; D S Chen
Journal:  J Infect Dis       Date:  1992-11       Impact factor: 5.226

8.  Peripheral blood leukocytes serve as a possible extrahepatic site for hepatitis C virus replication.

Authors:  H M Müller; E Pfaff; T Goeser; B Kallinowski; C Solbach; L Theilmann
Journal:  J Gen Virol       Date:  1993-04       Impact factor: 3.891

9.  Hepatic and extrahepatic hepatitis C virus replication in relation to response to interferon therapy.

Authors:  M G Saleh; C J Tibbs; J Koskinas; L M Pereira; A B Bomford; B C Portmann; I G McFarlane; R Williams
Journal:  Hepatology       Date:  1994-12       Impact factor: 17.425

10.  Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR.

Authors:  R E Lanford; D Chavez; F V Chisari; C Sureau
Journal:  J Virol       Date:  1995-12       Impact factor: 5.103
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  33 in total

1.  Distinct viral populations differentiate and evolve independently in a single perennial host plant.

Authors:  Chiraz Jridi; Jean-François Martin; Véronique Marie-Jeanne; Gérard Labonne; Stéphane Blanc
Journal:  J Virol       Date:  2006-03       Impact factor: 5.103

2.  Presence of hepatitis C virus (HCV) RNA in the genital tracts of HCV/HIV-1-coinfected women.

Authors:  Marek J Nowicki; Tomasz Laskus; Georgia Nikolopoulou; Marek Radkowski; Jeffrey Wilkinson; Wenbo B Du; Jorge Rakela; Andrea Kovacs
Journal:  J Infect Dis       Date:  2005-09-29       Impact factor: 5.226

3.  Evidence of distinct populations of hepatitis C virus in the liver and plasma of patients co-infected with HIV and HCV.

Authors:  Jason T Blackard; Gang Ma; Satarupa Sengupta; Christina M Martin; Eleanor A Powell; M Tarek Shata; Kenneth E Sherman
Journal:  J Med Virol       Date:  2014-04-30       Impact factor: 2.327

4.  Hepatitis C virus and peripheral blood mononuclear cell reservoirs Patricia Baré.

Authors:  Patricia Baré
Journal:  World J Hepatol       Date:  2009-10-31

5.  Identification of unique hepatitis C virus quasispecies in the central nervous system and comparative analysis of internal translational efficiency of brain, liver, and serum variants.

Authors:  Daniel M Forton; Peter Karayiannis; Nadiya Mahmud; Simon D Taylor-Robinson; Howard C Thomas
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

6.  Compartmentalization of hepatitis C virus (HCV) during HCV/HIV coinfection.

Authors:  Jason T Blackard; Yoichi Hiasa; Laura Smeaton; Denise J Jamieson; Irma Rodriguez; Kenneth H Mayer; Raymond T Chung
Journal:  J Infect Dis       Date:  2007-05-02       Impact factor: 5.226

7.  A viral protein mediates superinfection exclusion at the whole-organism level but is not required for exclusion at the cellular level.

Authors:  María Bergua; Mark P Zwart; Choaa El-Mohtar; Turksen Shilts; Santiago F Elena; Svetlana Y Folimonova
Journal:  J Virol       Date:  2014-07-16       Impact factor: 5.103

8.  L-SIGN (CD209L) and DC-SIGN (CD209) mediate transinfection of liver cells by hepatitis C virus.

Authors:  Emmanuel G Cormier; Robert J Durso; Fotini Tsamis; Lise Boussemart; Catherine Manix; William C Olson; Jason P Gardner; Tatjana Dragic
Journal:  Proc Natl Acad Sci U S A       Date:  2004-09-15       Impact factor: 11.205

9.  Persistence of hepatitis C virus in peripheral blood mononuclear cells of sustained viral responders to pegylated interferon and ribavirin therapy.

Authors:  Juan F Gallegos-Orozco; Jorge Rakela; Marianne J Rosati; Hugo E Vargas; Vijayan Balan
Journal:  Dig Dis Sci       Date:  2008-07-02       Impact factor: 3.199

10.  Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.

Authors:  J A McKeating; L Q Zhang; C Logvinoff; M Flint; J Zhang; J Yu; D Butera; D D Ho; L B Dustin; C M Rice; P Balfe
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103
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