OBJECTIVE: To evaluate the accuracy of a new staging criterion, submucosal linear enhancement (SLE) on gadolinium-diethylenetriamine-pentaacetic acid-enhanced T1-weighted magnetic resonance imaging (MRI) using an endorectal surface coil (endorectal enhanced MRI), and to compare the accuracy of this method with that of transurethral ultrasonography (TUUS). PATIENTS AND METHODS: The study included 71 patients with bladder tumours (63 men and eight women, mean age 65.5 years, range 31-85). The SLE coincided with abundant submucosal vascular beds, as reported in a previous study. When the SLE beneath the tumour maintained continuity, the tumour was diagnosed as superficial (</= T1), but if the SLE was interrupted by the tumour, the disease was considered invasive (>/= T2a). Superficial muscle invasion (less than half the muscle layer) and deep muscle invasion (more than half the muscle layer) were classified as T2a and T2b, respectively. When the tumour formed an extravesical mass, the tumour was classified as T3b. RESULTS: The staging accuracy for bladder tumours using SLE on endorectal-enhanced MRI or TUUS was 83% and 60%, respectively (P < 0.01). Using the SLE, muscle invasion of bladder tumour was diagnosed with an accuracy of 87%, a sensitivity of 91% and a specificity of 87%; this was significantly better than with TUUS (P < 0.01). CONCLUSION: The criterion of SLE on Gd-DTPA enhanced T1-weighted MRI using an endorectal surface coil is useful for staging bladder tumour, and the staging accuracy is significantly better than with TUUS.
OBJECTIVE: To evaluate the accuracy of a new staging criterion, submucosal linear enhancement (SLE) on gadolinium-diethylenetriamine-pentaacetic acid-enhanced T1-weighted magnetic resonance imaging (MRI) using an endorectal surface coil (endorectal enhanced MRI), and to compare the accuracy of this method with that of transurethral ultrasonography (TUUS). PATIENTS AND METHODS: The study included 71 patients with bladder tumours (63 men and eight women, mean age 65.5 years, range 31-85). The SLE coincided with abundant submucosal vascular beds, as reported in a previous study. When the SLE beneath the tumour maintained continuity, the tumour was diagnosed as superficial (</= T1), but if the SLE was interrupted by the tumour, the disease was considered invasive (>/= T2a). Superficial muscle invasion (less than half the muscle layer) and deep muscle invasion (more than half the muscle layer) were classified as T2a and T2b, respectively. When the tumour formed an extravesical mass, the tumour was classified as T3b. RESULTS: The staging accuracy for bladder tumours using SLE on endorectal-enhanced MRI or TUUS was 83% and 60%, respectively (P < 0.01). Using the SLE, muscle invasion of bladder tumour was diagnosed with an accuracy of 87%, a sensitivity of 91% and a specificity of 87%; this was significantly better than with TUUS (P < 0.01). CONCLUSION: The criterion of SLE on Gd-DTPA enhanced T1-weighted MRI using an endorectal surface coil is useful for staging bladder tumour, and the staging accuracy is significantly better than with TUUS.
Authors: Sungmin Woo; Valeria Panebianco; Yoshifumi Narumi; Francesco Del Giudice; Valdair F Muglia; Mitsuru Takeuchi; Soleen Ghafoor; Bernard H Bochner; Alvin C Goh; Hedvig Hricak; James W F Catto; Hebert Alberto Vargas Journal: Eur Urol Oncol Date: 2020-03-19
Authors: Valeria Panebianco; Yoshifumi Narumi; Ersan Altun; Bernard H Bochner; Jason A Efstathiou; Shaista Hafeez; Robert Huddart; Steve Kennish; Seth Lerner; Rodolfo Montironi; Valdair F Muglia; Georg Salomon; Stephen Thomas; Hebert Alberto Vargas; J Alfred Witjes; Mitsuru Takeuchi; Jelle Barentsz; James W F Catto Journal: Eur Urol Date: 2018-05-10 Impact factor: 20.096
Authors: Xiaopan Xu; Huanjun Wang; Yan Guo; Xi Zhang; Baojuan Li; Peng Du; Yang Liu; Hongbing Lu Journal: Front Oncol Date: 2021-07-15 Impact factor: 6.244