Literature DB >> 10611116

Ergotamine in the acute treatment of migraine: a review and European consensus.

P Tfelt-Hansen1, P R Saxena, C Dahlöf, J Pascual, M Láinez, P Henry, H Diener, J Schoenen, M D Ferrari, P J Goadsby.   

Abstract

Ergotamine has been used in clinical practice for the acute treatment of migraine for over 50 years, but there has been little agreement on its place in clinical practice. An expert group from Europe reviewed the pre-clinical and clinical data on ergotamine as it relates to the treatment of migraine. From this review, specific suggestions for the patient groups and appropriate use of ergotamine have been agreed. In essence, ergotamine, from a medical perspective, is the drug of choice in a limited number of migraine sufferers who have infrequent or long duration headaches and are likely to comply with dosing restrictions. For most migraine sufferers requiring a specific anti-migraine treatment, a triptan is generally a better option from both an efficacy and side-effect perspective.

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Year:  2000        PMID: 10611116     DOI: 10.1093/brain/123.1.9

Source DB:  PubMed          Journal:  Brain        ISSN: 0006-8950            Impact factor:   13.501


  54 in total

1.  The effect of rizatriptan, ergotamine, and their combination on human peripheral arteries: a double-blind, placebo-controlled, crossover study in normal subjects.

Authors:  Peer Tfelt-Hansen; Kaj Seidelin; Michael Stepanavage; Christopher Lines
Journal:  Br J Clin Pharmacol       Date:  2002-07       Impact factor: 4.335

2.  Risk of stroke, gangrene from ergot drug interactions.

Authors:  Eric Wooltorton
Journal:  CMAJ       Date:  2003-04-15       Impact factor: 8.262

3.  5-HT1B receptors, alpha2A/2C- and, to a lesser extent, alpha1-adrenoceptors mediate the external carotid vasoconstriction to ergotamine in vagosympathectomised dogs.

Authors:  Luis F Valdivia; David Centurión; Udayasankar Arulmani; Pramod R Saxena; Carlos M Villalón
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2004-06-29       Impact factor: 3.000

Review 4.  Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches.

Authors:  Peter J Goadsby
Journal:  Drugs       Date:  2005       Impact factor: 9.546

Review 5.  Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs.

Authors:  Sang-Min Lee; Jason M Booe; Augen A Pioszak
Journal:  Eur J Pharmacol       Date:  2015-05-14       Impact factor: 4.432

Review 6.  CADASIL: Treatment and Management Options.

Authors:  Anna Bersano; Gloria Bedini; Joshua Oskam; Caterina Mariotti; Franco Taroni; Silvia Baratta; Eugenio Agostino Parati
Journal:  Curr Treat Options Neurol       Date:  2017-09       Impact factor: 3.598

Review 7.  Revision of the classical dopamine D2 agonist pharmacophore based on an integrated medicinal chemistry, homology modelling and computational docking approach.

Authors:  N Krogsgaard-Larsen; K Harpsøe; J Kehler; C T Christoffersen; P Brøsen; T Balle
Journal:  Neurochem Res       Date:  2014-07-24       Impact factor: 3.996

8.  Acute Treatment of Migraine Headache.

Authors:  Marcelo E. Bigal; Richard B. Lipton
Journal:  Curr Treat Options Neurol       Date:  2003-11       Impact factor: 3.598

Review 9.  Indolealkylamines: biotransformations and potential drug-drug interactions.

Authors:  Ai-Ming Yu
Journal:  AAPS J       Date:  2008-05-03       Impact factor: 4.009

Review 10.  Migraine pathogenesis and state of pharmacological treatment options.

Authors:  Till Sprenger; Peter J Goadsby
Journal:  BMC Med       Date:  2009-11-16       Impact factor: 8.775

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