Literature DB >> 10601226

Mutations in catabolite control protein CcpA showing glucose-independent regulation in Bacillus megaterium.

E Küster-Schöck1, A Wagner, U Völker, W Hillen.   

Abstract

We identified five single amino acid exchanges in CcpA that lead to permanent repression of the xylose utilization genes in the absence of glucose. Other proteins from the CcpA regulon also show glucose-independent regulation in the mutants. The mutant CcpA proteins bind to the DNA target catabolite responsive elements without the corepressor HPr-Ser-P.

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Year:  1999        PMID： 10601226      PMCID： PMC94226          DOI： 10.1128/JB.181.24.7634-7638.1999

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  32 in total

1.  A family of bacterial regulators homologous to Gal and Lac repressors.

Authors:  M J Weickert; S Adhya
Journal:  J Biol Chem       Date:  1992-08-05       Impact factor: 5.157

2.  The phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus. 1. Amino-acid sequence of the phosphocarrier protein HPr.

Authors:  K Beyreuther; H Raufuss; O Schrecker; W Hengstenberg
Journal:  Eur J Biochem       Date:  1977-05-02

3.  Crystal structure of lac repressor core tetramer and its implications for DNA looping.

Authors:  A M Friedman; T O Fischmann; T A Steitz
Journal:  Science       Date:  1995-06-23       Impact factor: 47.728

4.  Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by alpha helices.

Authors:  M A Schumacher; K Y Choi; H Zalkin; R G Brennan
Journal:  Science       Date:  1994-11-04       Impact factor: 47.728

5.  Mutations in catabolite control protein CcpA separating growth effects from catabolite repression.

Authors:  E Küster; T Hilbich; M K Dahl; W Hillen
Journal:  J Bacteriol       Date:  1999-07       Impact factor: 3.490

6.  Catabolite repression of the xyl operon in Bacillus megaterium.

Authors:  T Rygus; W Hillen
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

7.  Catabolite repression of alpha-amylase gene expression in Bacillus subtilis involves a trans-acting gene product homologous to the Escherichia coli lacl and galR repressors.

Authors:  T M Henkin; F J Grundy; W L Nicholson; G H Chambliss
Journal:  Mol Microbiol       Date:  1991-03       Impact factor: 3.501

8.  Specificity of DNA binding activity of the Bacillus subtilis catabolite control protein CcpA.

Authors:  J H Kim; Z T Guvener; J Y Cho; K C Chung; G H Chambliss
Journal:  J Bacteriol       Date:  1995-09       Impact factor: 3.490

9.  A Clostridium acetobutylicum regulator gene (regA) affecting amylase production in Bacillus subtilis.

Authors:  S P Davison; J D Santangelo; S J Reid; D R Woods
Journal:  Microbiology       Date:  1995-04       Impact factor: 2.777

10.  Protein kinase-dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in gram-positive bacteria.

Authors:  J Deutscher; E Küster; U Bergstedt; V Charrier; W Hillen
Journal:  Mol Microbiol       Date:  1995-03       Impact factor: 3.501
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3.  Probing the regulatory effects of specific mutations in three major binding domains of the pleiotropic regulator CcpA of Bacillus subtilis.

Authors:  Ruud Detert Oude Weme; Gerald Seidel; Oscar P Kuipers
Journal:  Front Microbiol       Date:  2015-10-02       Impact factor: 5.640

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