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Literature DB >> 10598932

Determination of oxygen extraction ratios by magnetic resonance imaging.

J M Oja¹, J S Gillen, R A Kauppinen, M Kraut, P C van Zijl.

Abstract

The oxygen extraction ratio (OER) of a tissue describes the interplay between oxygen delivery and consumption and, as such, directly reflects the viability and activity of any organ. It is shown that OER can be quantified using a single magnetic resonance imaging observable, namely the relaxation time T2 of venous blood draining from the tissue. This principle is applied to study local OER changes in the brain on visual stimulation in humans, unambiguously demonstrating a mismatch between changes in blood flow and oxygen metabolism on activation.

Entities: Chemical Species

Mesh：

Substances：
Oxygen

Year: 1999 PMID： 10598932 DOI： 10.1097/00004647-199912000-00001

Source DB: PubMed Journal: J Cereb Blood Flow Metab ISSN： 0271-678X Impact factor: 6.200

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Cited

45 in total

1. Use of spin echo T(2) BOLD in assessment of cerebral misery perfusion at 1.5 T.

Authors: M Kavec; O H Gröhn; M I Kettunen; M J Silvennoinen; M Penttonen; R A Kauppinen
Journal: MAGMA Date: 2001-03 Impact factor: 2.310

2. Blood longitudinal (T1) and transverse (T2) relaxation time constants at 11.7 Tesla.

Authors: Ai-Ling Lin; Qin Qin; Xia Zhao; Timothy Q Duong
Journal: MAGMA Date: 2011-11-10 Impact factor: 2.310

3. Magnetic resonance imaging reveals slow-down of global cerebral oxygen metabolism in multiple sclerosis.

Authors: Risto A Kauppinen
Journal: J Cereb Blood Flow Metab Date: 2012-01-04 Impact factor: 6.200

4. Venous oxygenation mapping using velocity-selective excitation and arterial nulling.

Authors: Jia Guo; Eric C Wong
Journal: Magn Reson Med Date: 2012-01-31 Impact factor: 4.668

5. Does acute caffeine ingestion alter brain metabolism in young adults?

Authors: Feng Xu; Peiying Liu; James J Pekar; Hanzhang Lu
Journal: Neuroimage Date: 2015-01-30 Impact factor: 6.556

6. QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venular-targeted velocity-selective spin labeling.

Authors: D S Bolar; B R Rosen; A G Sorensen; E Adalsteinsson
Journal: Magn Reson Med Date: 2011-06-14 Impact factor: 4.668

Determination of oxygen extraction ratios by magnetic resonance imaging.

1. Use of spin echo T(2) BOLD in assessment of cerebral misery perfusion at 1.5 T.

2. Blood longitudinal (T1) and transverse (T2) relaxation time constants at 11.7 Tesla.

3. Magnetic resonance imaging reveals slow-down of global cerebral oxygen metabolism in multiple sclerosis.

4. Venous oxygenation mapping using velocity-selective excitation and arterial nulling.

5. Does acute caffeine ingestion alter brain metabolism in young adults?

6. QUantitative Imaging of eXtraction of oxygen and TIssue consumption (QUIXOTIC) using venular-targeted velocity-selective spin labeling.

7. Correction and optimization of a T2-based approach to map blood oxygenation in small cerebral veins.

8. Cerebral Oxygen Saturation in Children With Congenital Heart Disease and Chronic Hypoxemia.

9. Oxygen metabolism in ischemic stroke using magnetic resonance imaging.

10. Quantitative evaluation of oxygenation in venous vessels using T2-Relaxation-Under-Spin-Tagging MRI.