Literature DB >> 10597862

Assessing the cardiac safety of ebastine. Prologue.

D J Roberts1.   

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Year:  1999        PMID: 10597862     DOI: 10.2165/00002018-199921001-00001

Source DB:  PubMed          Journal:  Drug Saf        ISSN: 0114-5916            Impact factor:   5.606


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  11 in total

1.  Some observations on the cardiotoxic and drug interaction profiles of second generation antihistamines as measured in the guinea pig.

Authors:  D J Roberts; J Llenas
Journal:  Arzneimittelforschung       Date:  1996-08

2.  Cardiotoxic and drug interaction profile of the second generation antihistamines ebastine and terfenadine in an experimental animal model of torsade de pointes.

Authors:  J A Hey; M del Prado; W Kreutner; R W Egan
Journal:  Arzneimittelforschung       Date:  1996-02

3.  Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects.

Authors:  J A Hey; M del Prado; J Sherwood; W Kreutner; R W Egan
Journal:  Arzneimittelforschung       Date:  1996-02

4.  Pharmacology of the specific histamine H1-antagonist astemizole.

Authors:  F H Awouters; C J Niemegeers; P A Janssen
Journal:  Arzneimittelforschung       Date:  1983

5.  The role of ketoconazole in the QTc interval prolonging effects of H1-antihistamines in a guinea-pig model of arrhythmogenicity.

Authors:  J Gras; J Llenas; J M Palacios; D J Roberts
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

Review 6.  In vitro electrophysiological detection of iatrogenic arrhythmogenicity.

Authors:  M M Adamantidis; P Kerram; B A Dupuis
Journal:  Fundam Clin Pharmacol       Date:  1994       Impact factor: 2.748

7.  Terfenadine, the first non-sedating antihistamine.

Authors:  J K Woodward; N L Munro
Journal:  Arzneimittelforschung       Date:  1982

8.  Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs.

Authors:  J A Hey; M Del Prado; F M Cuss; R W Egan; J Sherwood; C C Lin; W Kreutner
Journal:  Clin Exp Allergy       Date:  1995-10       Impact factor: 5.018

9.  Mechanism of the cardiotoxic actions of terfenadine.

Authors:  R L Woosley; Y Chen; J P Freiman; R A Gillis
Journal:  JAMA       Date:  1993 Mar 24-31       Impact factor: 56.272

10.  Effects of terfenadine and its metabolites on a delayed rectifier K+ channel cloned from human heart.

Authors:  D Rampe; B Wible; A M Brown; R C Dage
Journal:  Mol Pharmacol       Date:  1993-12       Impact factor: 4.436

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