Literature DB >> 10591201

Alzheimer's disease. A firm base for drug development.

B De Strooper, G König.   

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Year:  1999        PMID: 10591201     DOI: 10.1038/44973

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


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  13 in total

Review 1.  Spotlight on BACE: the secretases as targets for treatment in Alzheimer disease.

Authors:  C Dingwall
Journal:  J Clin Invest       Date:  2001-11       Impact factor: 14.808

Review 2.  Genetically engineered models relevant to neurodegenerative disorders: their value for understanding disease mechanisms and designing/testing experimental therapeutics.

Authors:  P C Wong; H Cai; D R Borchelt; D L Price
Journal:  J Mol Neurosci       Date:  2001-10       Impact factor: 3.444

3.  Developing consensus 3D-QSAR and pharmacophore models for several beta-secretase, farnesyl transferase and histone deacetylase inhibitors.

Authors:  Hsin-Yuan Wei; Guan-Ju Chen; Chih-Lun Chen; Thy-Hou Lin
Journal:  J Mol Model       Date:  2011-05-12       Impact factor: 1.810

4.  Inhibition of amyloid precursor protein secretases reduces recovery after spinal cord injury.

Authors:  Ahdeah Pajoohesh-Ganji; Mark P Burns; Sonali Pal-Ghosh; Gauri Tadvalkar; Nicole G Hokenbury; Mary Ann Stepp; Alan I Faden
Journal:  Brain Res       Date:  2014-03-11       Impact factor: 3.252

Review 5.  gamma-Secretase inhibitors as molecular probes of presenilin function.

Authors:  M S Wolfe
Journal:  J Mol Neurosci       Date:  2001-10       Impact factor: 3.444

6.  Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.

Authors:  Dongming Cai; William J Netzer; Minghao Zhong; Yixin Lin; Guangwei Du; Michael Frohman; David A Foster; Sangram S Sisodia; Huaxi Xu; Fred S Gorelick; Paul Greengard
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-31       Impact factor: 11.205

Review 7.  Notch: from neural development to neurological disorders.

Authors:  Justin D Lathia; Mark P Mattson; Aiwu Cheng
Journal:  J Neurochem       Date:  2008-12       Impact factor: 5.372

8.  Synthesis and evaluation of 2-(3'-iodo-4'-aminophenyl)-6-hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease.

Authors:  Yanming Wang; William E Klunk; Guo-Feng Huang; Manik L Debnath; Daniel P Holt; Chester A Mathis
Journal:  J Mol Neurosci       Date:  2002 Aug-Oct       Impact factor: 3.444

9.  γ-Secretase-Dependent Proteolysis of Transmembrane Domain of Amyloid Precursor Protein: Successive Tri- and Tetrapeptide Release in Amyloid β-Protein Production.

Authors:  Mako Takami; Satoru Funamoto
Journal:  Int J Alzheimers Dis       Date:  2012-12-31

10.  Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial.

Authors:  Hui Chen; Shuai Liu; Lu Ji; Tianfeng Wu; Yong Ji; Yuying Zhou; Miaoyan Zheng; Meilin Zhang; Weili Xu; Guowei Huang
Journal:  Mediators Inflamm       Date:  2016-06-02       Impact factor: 4.711

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